推荐产品
质量水平
方案
≥99%
表单
liquid
折射率
n20/D 1.561 (lit.)
沸点
273 °C (lit.)
mp
9-12 °C (lit.)
溶解性
alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
water: insoluble(lit.)
密度
1.254 g/mL at 25 °C (lit.)
官能团
nitro
SMILES字符串
COc1ccccc1[N+]([O-])=O
InChI
1S/C7H7NO3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5H,1H3
InChI key
CFBYEGUGFPZCNF-UHFFFAOYSA-N
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一般描述
2-Nitroanisole (2-methoxynitrobenzene is an industrial and environmental pollutant causing tumors of the urinary bladder in rats and mice. Tumorigenic potential of 2-nitroanisole has been evaluated by host-mediated in vitro and in vivo assay.
应用
2-Nitroanisole has been employed as solvatochromic probe to examine cybotactic region of pure and mixed supercritical fluid solvent systems.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Y Miura et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 100(2), 249-252 (1991-01-01)
1. The cytochrome P-450 content (0.75 +/- 0.13 nmol/mg microsomal protein) in musk shrew (suncus, Suncus murinus) liver microsomes was lower than that (1.30 +/- 0.26) in rat liver microsomes, but it is approximately the same level as in the
Effects of physical binding of o-Nitroanisole with feed upon its systemic availability in male F344 rats.
J H Yuan et al.
Bulletin of environmental contamination and toxicology, 47(1), 152-159 (1991-07-01)
M J Miller et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(5), 527-531 (1985-09-01)
The pharmacokinetics and metabolism of o-nitroanisole (ONA) were studied in male Fischer 344 rats. Three dose levels of [14C]ONA (5.0, 50, or 500 mg/kg) were administered orally to rats and daily excreta were analyzed for 14C. Since the highest dose
Markéta Miksanová et al.
Chemical research in toxicology, 17(5), 663-671 (2004-05-18)
2-Nitroanisole (2-NA) is an important industrial pollutant and a potent carcinogen for rodents. Determining the capability of humans to metabolize 2-NA and understanding which human cytochrome P450 (P450) enzymes are involved in its activation and/or detoxification are important to assess
Marie Stiborová et al.
Interdisciplinary toxicology, 2(1), 24-27 (2009-03-01)
An aromatic amine, o-anisidine (2-methoxyaniline) and its oxidative counterpart, 2-nitroanisole (2-methoxynitrobenzene), are the industrial and environmental pollutants causing tumors of the urinary bladder in rats and mice. Both carcinogens are activated to the same proximate carcinogenic metabolite, N-(2-methoxyphenyl)hydroxylamine, which spontaneously
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