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Merck
CN

235210

Sigma-Aldrich

(1R,2S)-(-)-N-甲基麻黄碱

99%

别名:

(-)-(1R,2S)-2-二甲基氨基-1-苯丙醇, (-)-N-甲基麻黄碱, [R-(R*,S*)]-α-[1-(二甲基氨基)乙基]苯甲醇

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About This Item

线性分子式:
C6H5CH(OH)CH(CH3)N(CH3)2
CAS号:
分子量:
179.26
Beilstein:
3031197
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

solid

旋光性

[α]21/D −29.2°, c = 5 in methanol

mp

86-88 °C (lit.)

储存温度

2-8°C

SMILES字符串

C[C@@H]([C@H](O)c1ccccc1)N(C)C

InChI

1S/C11H17NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9,11,13H,1-3H3/t9-,11-/m0/s1

InChI key

FMCGSUUBYTWNDP-ONGXEEELSA-N

应用

拆分剂。手性支持电解质的前体、相转移催化剂和还原剂。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

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Chemistry Letters (Jpn), 981-981 (1980)
Angewandte Chemie (International Edition in English), 23, 165-165 (1984)
María José Ojeda-Montes et al.
Future medicinal chemistry, 9(18), 2129-2146 (2017-11-28)
Extracts from Ephedra species have been reported to be effective as antidiabetics. A previous in silico study predicted that ephedrine and five ephedrine derivatives could contribute to the described antidiabetic effect of Ephedra extracts by inhibiting dipeptidyl peptidase IV (DPP-IV).
Guoyi Ma et al.
The Journal of pharmacology and experimental therapeutics, 322(1), 214-221 (2007-04-05)
Ephedra species of plants have both beneficial and adverse effects primarily associated with the presence of ephedrine alkaloids. Few reports have appeared that examine the direct actions of ephedrine alkaloids on human subtypes of adrenergic receptors (ARs). In the present
H J Lee et al.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 30(6), 563-566 (2010-08-13)
No information is currently available on the safety of methylephedrine, a component of various cold medications available in South Korea. With previous approval by an Institutional Review Board, 349 women inadvertently exposed to methylephedrine during the 1st trimester of pregnancy

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