检测方案
≥73% (HPLC)
质量水平
形式
powder
组成
Dye content, 75%
颜色
brown to very dark brown
green to very dark green
溶解性
methanol: 1 mg/mL
λmax
554 nm
ε (消光系数)
≥85000 at 554-560 nm in 0.1 M NaOH in methanol at 0.005 g/L
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1
InChI
1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
InChI key
SXQCTESRRZBPHJ-UHFFFAOYSA-M
一般描述
磺酰罗丹明B（SRB）是一种亮粉色氨基甲氧杂蒽类染料。磺酰罗丹明B（SRB）测定被广泛用于 体外 细胞毒性筛选。SRB以化学计量方式与细胞的蛋白质成分结合。因此，从染色细胞中提取的染料量与细胞质量成正比。SRB还可用于细胞密度测定。
应用
磺酰罗丹明B已被用作MCF-7（人乳腺癌细胞系）细胞增殖实验的染料。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals
Kj?rstad MB
Reproductive Toxicology, 30, 573-582 (2010)
Sulforhodamine B colorimetric assay for cytotoxicity screening
Vichai V
Nature Protocols, 1, 1112?1116-1112?1116 (2006)
Christian A Ruge et al.
Colloids and surfaces. B, Biointerfaces, 139, 219-227 (2016-01-01)
The conversion of colloidal drug carriers/polymeric nanoparticles into dry microparticulate powders (e.g., by spray-drying) is a prominent approach to overcome the aerodynamic limitations of these formulations for delivery via inhalation. However, to what extent such nano-embedded microparticles disintegrate into individual/intact
Samantha N Andrews et al.
Pharmaceutical research, 30(4), 1099-1109 (2012-12-01)
Most methods to increase transdermal drug delivery focus on increasing stratum corneum permeability, without addressing the need to increase permeability of viable epidermis. Here, we assess the hypothesis that viable epidermis offers a significant permeability barrier that becomes rate limiting
Anna Jaśkiewicz et al.
Journal of clinical medicine, 8(5) (2019-05-19)
The present study is centered on molecular mechanisms of the cytoprotective effect of geranylgeraniol (GGOH) in skeletal muscle harmed by statin-associated myopathy (SAM). GGOH via autophagy induction was purportedly assumed to prevent skeletal muscle viability impaired by statins, atorvastatin (ATR)
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