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Merck
CN

227935

Sigma-Aldrich

天青B

prepared by direct synthesis

别名:

N,N,N′-三甲基硫堇, 亚甲基天青, 天青I

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About This Item

经验公式(希尔记法):
C15H16ClN3S
CAS号:
分子量:
305.83
颜色索引号:
52010
Beilstein:
3922630
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

质量水平

方案

>85.0% (HPLC)

表单

powder

mp

205-210 °C (dec.) (lit.)

溶解性

water: 1 mg/mL, blue to very deep blue

λmax

648 nm

ε (消光系数)

≥13000 at 241-247 nm
≥36000 at 287-293 nm
≥67000 at 638-644 nm

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

C[N+](C)=C(C=C1)C=C(C1=N2)SC3=C2C=CC(NC)=C3.[Cl-]

InChI

1S/C15H15N3S.ClH/c1-16-10-4-6-12-14(8-10)19-15-9-11(18(2)3)5-7-13(15)17-12;/h4-9H,1-3H3;1H

InChI key

DNDJEIWCTMMZBX-UHFFFAOYSA-N

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应用

天青B已用于M′Fadyean染色,用于炭疽杆菌( Bacillus anthracis)荚膜的染色观察。

生化/生理作用

天青B是一种阳离子染料,作为瑞氏染色剂(Romanowsky stain)的一部分,可用于血涂片染色。也可用于核酸和木质素的定位显色。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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Barbara J. Bain, Imelda Bates, Mike A Laffan
Dacie and Lewis Practical Haematology (2016)
A simple, reliable M'Fadyean stain for visualizing the Bacillus anthracis capsule
Owen MP
Journal of Microbiological Methods, 92, 264-269 (2013)
U.S. Forest Service research note FPL (1964)
Anél Petzer et al.
Toxicology and applied pharmacology, 258(3), 403-409 (2011-12-27)
Methylene blue (MB) has been shown to act at multiple cellular and molecular targets and as a result possesses diverse medical applications. Among these is a high potency reversible inhibition of monoamine oxidase A (MAO-A) that may, at least in
C J Kligora et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 12(12), 1143-1147 (2000-01-05)
Distinguishing heavily pigmented melanocytes from melanophages on routine hematoxylin and eosin slides can be difficult. Melanin bleaching with potassium permanganate solution is a traditional means of removing melanin from tissues and can be used before immunohistochemical staining to remove any

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