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Merck
CN

226351

Sigma-Aldrich

N-羟基马来酰亚胺

97%, for peptide synthesis

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别名:
1-羟基吡咯-2,5-二酮
经验公式(希尔记法):
C4H3NO3
CAS号:
分子量:
113.07
Beilstein:
1524594
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

形式

solid

反应适用性

reaction type: Addition Reactions

mp

130-133 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

ON1C(=O)C=CC1=O

InChI

1S/C4H3NO3/c6-3-1-2-4(7)5(3)8/h1-2,8H

InChI key

BUXKULRFRATXSI-UHFFFAOYSA-N

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一般描述

N-羟基马来酰亚胺(NHMI)是一种有机化合物,广泛用作有机合成的氧化剂。常用于将硫醇选择性氧化为二硫化物,也用于α,β-不饱和羰基化合物的合成。还可作为Michael受体,用于多肽和蛋白质的合成。

应用

N-羟基马来酰亚胺可作为氧化剂,原位生成N-羟基苯胺类物质,这种物质是N-取代苯胺和羟胺衍生物经由选择性偶联反应高效合成芳肟的重要中间体。

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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