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Merck
CN

22550

Sigma-Aldrich

2-甲基喹啉

≥95.0% (GC)

别名:

喹哪啶

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About This Item

经验公式(希尔记法):
C10H9N
CAS号:
分子量:
143.19
Beilstein:
110309
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

≥95.0% (GC)

表单

liquid

折射率

n20/D 1.612 (lit.)

沸点

105-107 °C/10 mmHg (lit.)
248 °C (lit.)

mp

−9-−3 °C (lit.)

溶解性

chloroform: soluble(lit.)
diethyl ether: soluble(lit.)
water: insoluble(lit.)

密度

1.058 g/mL at 25 °C (lit.)

SMILES字符串

Cc1ccc2ccccc2n1

InChI

1S/C10H9N/c1-8-6-7-9-4-2-3-5-10(9)11-8/h2-7H,1H3

InChI key

SMUQFGGVLNAIOZ-UHFFFAOYSA-N

基因信息

human ... CYP1A2(1544)

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一般描述

喹哪啶是一种有机化合物,由巴豆醛和苯胺在脱氢剂存在下与硫酸通过 Skraup 方法制备。以喹那啶为原料合成了几种染料,包括三聚辛氰染料、频哪腈染料、乙烯基染料、喹啉酮染料和喹那啶红。此外,它还用于生产药品、pH 指示剂、食品着色剂、油溶性染料和其他化合物。

应用

喹哪啶可用于:
  • 在方胺染料(喹哪啶基方胺染料)的制备中,方胺染料具有重要的生物学意义,可作为金属离子传感器。
  • 制备 pH 敏感的比色化学传感器。

特点和优势

2-甲基喹啉是可生物降解的。

注意

储存后可能变为棕色

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

174.2 °F - closed cup

闪点(°C)

79 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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J L Allen et al.
Veterinary and human toxicology, 28 Suppl 1, 21-24 (1986-01-01)
Residue concentrations of drugs that are administered to fish by bath immersion are related primarily to passage of the drugs across the gills. The elimination of these chemicals by fish can be mediated by biotransformation, but the route of elimination
Tasneem G Kazi et al.
Journal of hazardous materials, 172(2-3), 780-785 (2009-08-12)
A new method is reported for the separation of aluminum ions [Al(III)] from interfering elements in parenteral and pharmaceutical solutions (PS) and bottled mineral water (BMW) samples, through solid-phase extraction with 2-methyl-8-hydroxyquinoline (quinaldine) adsorbed onto activated silica gel. While the
Heiko Niewerth et al.
BMC genomics, 13, 534-534 (2012-10-09)
Bacteria of the genus Arthrobacter are ubiquitous in soil environments and can be considered as true survivalists. Arthrobacter sp. strain Rue61a is an isolate from sewage sludge able to utilize quinaldine (2-methylquinoline) as sole carbon and energy source. The genome
Daniela Pucci et al.
Chemical communications (Cambridge, England), (19)(19), 2254-2256 (2008-05-09)
The synthesis of the first gallium(III)-based liquid crystal has been achieved grafting around the metal centre two chelating 2-methylquinolin-8-olate anions and one monodentate 3,4,5-tris(hexadecyloxy)benzoyloxy ligand, allowing the resulting complex to be a soft luminescent material with the typical high quantum
H Cope et al.
European journal of medicinal chemistry, 41(10), 1124-1143 (2006-06-20)
Transmissible spongiform encephalopathies (TSEs) are thought to arise from aggregation of a protease resistant protein denoted PrP(Sc), which is a misfolded isoform of the normal cellular prion protein PrP(C). Using virtual high-throughput screening we have selected structures analogous to acridine

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