所有图片(2)
About This Item
经验公式（希尔记法）:
C12H12O4
CAS号:
分子量:
220.22
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
等级
technical grade
表单
powder
mp
139-144 °C (lit.)
溶解性
chloroform: soluble 5%, clear, yellow-brown
官能团
carboxylic acid
ketone
SMILES字符串
COc1ccc2C(=O)CC(CC(O)=O)c2c1
InChI
1S/C12H12O4/c1-16-8-2-3-9-10(6-8)7(4-11(9)13)5-12(14)15/h2-3,6-7H,4-5H2,1H3,(H,14,15)
InChI key
QOTZOFGBBCMWEP-UHFFFAOYSA-N
一般描述
The 5-methoxy-1-indanone-3-acetic acid derivatives are potent inhibitors of chymotrypsin-like activity of the 20S proteasome.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
R T Lum et al.
Bioorganic & medicinal chemistry letters, 8(3), 209-214 (1999-01-01)
Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high selectivity for the chymotrypsin-like activity of the 20S proteasome.
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