所有图片(3)
About This Item
线性分子式:
C6H5CONHCH(OH)CO2H
CAS号:
分子量:
195.17
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
检测方案
98%
mp
211 °C (dec.) (lit.)
SMILES字符串
OC(NC(=O)c1ccccc1)C(O)=O
InChI
1S/C9H9NO4/c11-7(10-8(12)9(13)14)6-4-2-1-3-5-6/h1-5,8,12H,(H,10,11)(H,13,14)
InChI key
GCWCVCCEIQXUQU-UHFFFAOYSA-N
一般描述
α-Hydroxyhippuric acid, nonpeptidic substrate, forms complex with peptidyl-α-hydroxyglycine α-amidating lyase catalytic core.
应用
α-Hydroxyhippuric acid was used in the synthesis of benzamide by the enzyme-catalyzed dealkylation reaction.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A G Katopodis et al.
Biochemistry, 29(26), 6115-6120 (1990-07-03)
We report here the isolation of a novel enzyme from bovine neurointermediate pituitary which catalyzes the conversion of alpha-hydroxybenzoylglycine to benzamide. This enzyme, termed HGAD (alpha-hydroxyglycine amidating dealkylase), is a soluble protein with an apparent molecular mass of 45 kDa
Xiaoning Wang et al.
Journal of proteome research, 11(7), 3838-3847 (2012-05-26)
Cirrhosis is a common and terminal outcome of many chronic liver conditions. A urinary metabonomic study using gas chromatography-mass spectrometry (GC-MS) and ultra performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOFMS) was carried out to elucidate the pathophysiological basis of posthepatitis
Eduardo E Chufán et al.
Structure (London, England : 1993), 17(7), 965-973 (2009-07-17)
Many neuropeptides and peptide hormones require amidation of their carboxy terminal for full biological activity. The enzyme peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL; EC 4.3.2.5) catalyzes the second and last step of this reaction, N-dealkylation of the peptidyl-alpha-hydroxyglycine to generate the alpha-amidated
Brett Ronald Cutler et al.
International journal of cardiology, 261, 155-158 (2018-03-17)
Glycosaminoglycan (GAG), a major component of the endothelial glycocalyx, is severely perturbed in diabetic vasculature leading to endothelial inflammation and vascular disease in diabetes. We tested the hypothesis that blueberry metabolites (BBM) ameliorate endothelial inflammation in diabetic endothelial cells (ECs)
R Kulathila et al.
Archives of biochemistry and biophysics, 311(1), 191-195 (1994-05-15)
The conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides occurs in two distinct reactions, both of which are catalyzed by bifunctional peptidylglycine alpha-amidating enzyme. The first step is the alpha-hydroxylation of the C-terminal glycine residue and the second step
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