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Merck
CN

223867

Sigma-Aldrich

2,6-二异氰酸甲苯酯

97%

别名:

2-甲基-间亚苯基二异氰酸酯

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About This Item

线性分子式:
CH3C6H3(NCO)2
CAS号:
分子量:
174.16
Beilstein:
2211546
EC 号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23

质量水平

方案

97%

表单

liquid

自燃温度

>1148 °F

折射率

n20/D 1.571 (lit.)

沸点

129-133 °C/18 mmHg (lit.)

密度

1.225 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

Cc1c(cccc1N=C=O)N=C=O

InChI

1S/C9H6N2O2/c1-7-8(10-5-12)3-2-4-9(7)11-6-13/h2-4H,1H3

InChI key

RUELTTOHQODFPA-UHFFFAOYSA-N

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象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 2 Inhalation - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

闪点(°F)

230.0 °F - closed cup

闪点(°C)

110 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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G Sesana et al.
American Industrial Hygiene Association journal, 52(5), 183-186 (1991-05-01)
A new sampling system is presented that uses solid sorbent media contained in a tube for the determination of airborne isocyanates (2.4-2.6 toluene diisocyanate, hexamethylene diisocyanate, and 4.4' diaminodiphenylmethane diisocyanate). The method is compared with the National Institute for Occupational
P Carbonnelle et al.
The Analyst, 121(5), 663-669 (1996-05-01)
In recent years, epidemiological evidence that exposure to toluene diisocyanate (TDI) is associated with adverse health effects has led to the development of useful analytical methods for the biological monitoring of TDI. In this paper, an HPLC method is presented
B W Day et al.
Chemical research in toxicology, 9(3), 568-573 (1996-04-01)
Guinea pig hemoglobin (Hb) adducts of 2,4- and 2,6-toluene diisocyanate (2,4- and 2,6-TDI) were individually prepared, each at a Hb tetramer to diisocyanate ratio of 1:1, and compared with adducts of Hb from animals exposed to 1 ppm 2,4-TDI vapor.
B W Day et al.
Chemical research in toxicology, 10(4), 424-431 (1997-04-01)
During our ongoing studies of the reactions of toluene diisocyanate (2,4- and 2,6-diisocyanatotoluene, TDI) in vivo, it became apparent that reactive form(s) of these diisocyanates reach(es) the circulatory system after passage through the respiratory system. Based on recent work by
J Huang et al.
Archives of toxicology, 67(6), 373-378 (1993-01-01)
Groups of guinea pigs were exposed via inhalation to toluene diisocyanate (TDI) ranging from 0.02 to 1.0 ppm for 3 h/day on 5 consecutive days. Three weeks later, guinea pigs were challenged with TDI-GSA conjugates. Evaluations were based on TDI

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