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Merck
CN

223859

Sigma-Aldrich

(1,3-二氧环戊基-2-甲基)三苯基溴化膦

98%

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经验公式(希尔记法):
C22H24BrO2P
CAS号:
分子量:
431.30
EC 号:
MDL编号:
UNSPSC代码:
12352107
PubChem化学物质编号:
NACRES:
NA.22

检测方案

98%

反应适用性

reaction type: C-C Bond Formation

mp

193-195 °C (lit.)

SMILES字符串

[Br-].C1COC(C[P+](c2ccccc2)(c3ccccc3)c4ccccc4)O1

InChI

1S/C22H22O2P.BrH/c1-4-10-19(11-5-1)25(18-22-23-16-17-24-22,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15,22H,16-18H2;1H/q+1;/p-1

InChI key

FRHRVQQUICVJDG-UHFFFAOYSA-M

应用

Reactant for:
  • Preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione
  • Microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II
  • Preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands
  • Synthesis and antitumor agents
  • Regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Ying Li et al.
Chemistry, an Asian journal, 12(16), 2098-2103 (2017-05-31)
The development of a fluorescent probe to distinguish between cysteine (Cys) and homocysteine (Hcy) is always a challenge owing to their structural similarity, and the simultaneous detection of Cys and Hcy by utilizing different emission channels is especially difficult. In

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