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Merck
CN

221074

Sigma-Aldrich

顺式-2,4,5-三甲氧基-1-丙烯基苯

70%

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别名:
β-细辛脑, 顺式-细辛脑, 顺式-细辛醚, 顺式-2,4,5-三甲氧基-1-丙烯基苯
线性分子式:
(CH3O)3C6H2CH=CHCH3
CAS号:
分子量:
208.25
Beilstein:
1910605
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

质量水平

检测方案

70%

形式

liquid

折射率

n20/D 1.558 (lit.)

密度

1.073 g/mL at 25 °C (lit.)

SMILES字符串

[H]\C(C)=C(/[H])c1cc(OC)c(OC)cc1OC

InChI

1S/C12H16O3/c1-5-6-9-7-11(14-3)12(15-4)8-10(9)13-2/h5-8H,1-4H3/b6-5-

InChI key

RKFAZBXYICVSKP-WAYWQWQTSA-N

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一般描述

顺式-2,4,5-三甲氧基-1-丙烯基苯是一种抗生素,是使用各种色谱方法从石菖蒲提取物中分离得到的

应用

顺式-2,4,5-三甲氧基-1-丙烯基苯(β-Asarone)用于制备:
  • 2,4,5-三甲氧基肉桂醛和 2,4,5-三甲氧基肉桂基甲酰腙
  • 1-(2,4,5-三甲氧基苯基)-1,2-二羟基丙烷

其他说明

残留有反式(α-细辛醚)

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Jee Yeon Lee et al.
Journal of agricultural and food chemistry, 52(4), 776-780 (2004-02-19)
An antifungal substance was isolated from the extract of Acorus gramineus using various chromatographic procedures. The antibiotic was identified as beta-asarone, cis-2,4,5-trimethoxy-1-propenylbenzene, on the basis of the high-resolution EI-mass, NMR, and UV spectral data. Beta-asarone completely inhibited mycelial growth of
Arun K Sinha et al.
Journal of natural products, 65(5), 764-765 (2002-05-25)
Oxidation of beta-asarone (2) with DDQ gave trans-2,4,5-trimethoxycinnamaldehyde (3), which on treatment with p-toluenesulfonyl hydrazine provided corresponding alpha,beta-unsaturated hydrazone derivative (4). Reduction of 4 with sodium borohydride in acetic acid afforded gamma-asarone (1) in 43% yield.
A K Sinha et al.
Natural product letters, 15(6), 439-444 (2002-02-13)
1-(2,4,5-Trimethoxyphenyl)-1,2-dihydroxypropane (2), a natural phenylpropanoid occurring in Piper clusii, has been synthesized for the first time from toxic beta-asarone (1) of Acorus calamus with osmium tetroxide, while 1 with osmium tetroxide (catalytic amount) in presence of sodium metaperiodate furnished the
Qi-Xiong Chen et al.
Biological & pharmaceutical bulletin, 36(1), 23-30 (2012-10-19)
For centuries, extracts of Acorus gramineus have been used extensively in traditional Chinese medicine for the treatment, management, and/or control of human ailments, including central nervous system disorders such as convulsions and epilepsy. In the present study, we investigated the
Jadwiga Marczewska et al.
Acta poloniae pharmaceutica, 70(2), 349-354 (2013-04-26)
In our previous paper we examined mutagenic and genotoxic activity of 4 alpha-asarone isomers 2-5 exhibiting relatively high hypolipidemic activity. In the present paper, we examined genotoxic activity of alpha-asarone and its isomers as the ability to damage cellular DNA

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