InChI key
HQRSUIDICNOLPX-UHFFFAOYSA-M
InChI
1S/C13H16NO5.Hg.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;1H2/q;+1;/p-1
SMILES string
COC(CNC(=O)c1ccccc1OCC(O)=O)C[Hg]O
assay
97%
mp
192-193 °C (dec.) (lit.)
法规信息
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Georgiy A Belogurov et al.
The Journal of biological chemistry, 277(25), 22209-22214 (2002-04-17)
H(+)-translocating pyrophosphatase (H(+)-PPase) of the photosynthetic bacterium Rhodospirillum rubrum was expressed in Escherichia coli C43(DE3) cells. Recombinant H(+)-PPase was observed in inner membrane vesicles, where it catalyzed both PP(i) hydrolysis coupled with H(+) transport into the vesicles and PP(i) synthesis.
Anssi M Malinen et al.
The Journal of biological chemistry, 279(26), 26811-26816 (2004-04-27)
H(+)-pyrophosphatase (H(+)-PPase) catalyzes pyrophosphate-driven proton transport against the electrochemical potential gradient in various biological membranes. All 50 of the known H(+)-PPase amino acid sequences contain four invariant glutamate residues. In this study, we use site-directed mutagenesis in conjunction with functional
History of heart failure.
Hector O Ventura
Congestive heart failure (Greenwich, Conn.), 12(3), 178-178 (2006-06-09)
Noemí García et al.
Cell biochemistry and biophysics, 49(2), 84-90 (2007-10-02)
The purpose of this work was addressed to provide new information on the effect of thiol reagents on mitochondrial non-specific pore opening, and its response to cyclosporin A (CSA). To meet this proposal phenylarsine oxide (PHA) and mersalyl were employed
Manuel Gutiérrez-Aguilar et al.
Archives of biochemistry and biophysics, 494(2), 184-191 (2009-12-10)
The mitochondrial permeability transition (PT) involves the opening of a mitochondrial unselective channel (MUC) resulting in membrane depolarization and increased permeability to ions. PT has been observed in many, but not all eukaryotic species. In some species, PT has been
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