220051
N-碘代琥珀酰亚胺
95%
别名:
1-iodo-pyrrolidine-2,5-dione, 1-iodoazolidine-2,5-dione, NIS, succiniodimide
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关于此项目
经验公式（希尔记法）:
C4H4INO2
化学文摘社编号:
分子量:
224.98
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-221-6
Beilstein/REAXYS Number:
113917
MDL number:
Assay:
95%
Form:
powder
InChI key
LQZMLBORDGWNPD-UHFFFAOYSA-N
InChI
1S/C4H4INO2/c5-6-3(7)1-2-4(6)8/h1-2H2
SMILES string
IN1C(=O)CCC1=O
assay
95%
form
powder
mp
202-206 °C (lit.)
functional group
imide
storage temp.
2-8°C
Quality Level
Application
从 1,6-二炔经过高效的两步工艺制备的高取代的碘苯。与 TFA 一起使用，将硫苷化学选择性地水解为 1-羟基糖苷。从烯烃和苯亚磺酸合成乙烯砜。
signalword
Warning
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
hcodes
Hazard Classifications
Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1B
Yoshihiko Yamamoto et al.
Journal of the American Chemical Society, 128(25), 8336-8340 (2006-06-22)
Highly substituted iodobenzenes were efficiently and regioselectively synthesized from readily available 1,6-diynes via two-step process consisting of silver-catalyzed Csp-H iodination and subsequent ruthenium-catalyzed [2 + 2 + 2] cycloaddition of resultant iododiynes. Some of the obtained iodobenzenes were subjected to
Abby J Isaacs et al.
The Journal of thoracic and cardiovascular surgery, 149(5), 1262-1269 (2015-03-21)
Substantial controversy surrounds the choice between a mechanical versus bioprosthetic prosthesis for aortic valve replacement (AVR), based on age. This study aims to investigate national trends and in-hospital outcomes of the 2 prosthesis choices. All patients aged >18 years in
Canadian Journal of Chemistry, 84, 66-66 (2006)
Jasper Dinkelaar et al.
Carbohydrate research, 341(10), 1723-1729 (2006-04-06)
A variety of thioglycosides are chemoselectively hydrolyzed to the corresponding 1-hydroxy glycosides using equimolar amounts of NIS/TFA as promoter systems.
Mark C Dobish et al.
Journal of the American Chemical Society, 134(14), 6068-6071 (2012-04-03)
Highly enantioselective halolactonizations have been developed that employ a chiral proton catalyst-N-iodosuccinimide (NIS) reagent system in which the Brønsted acid is used at catalyst loadings as low as 1 mol %. An approach that modulates the achiral counterion (equimolar to
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