质量水平
检测方案
99%
形式
solid
mp
86-87 °C (lit.)
SMILES字符串
CC(C)C(O)C(O)=O
InChI
1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)
InChI key
NGEWQZIDQIYUNV-UHFFFAOYSA-N
一般描述
采用毛细管电泳法，以 2-羟丙基-β-环糊精为拆分剂，研究了 2-羟基-3-甲基丁酸的手性拆分。
应用
采用 2-羟基-3-甲基丁酸作为内标物分析乙二醇 (EG) 和 γ-全血中的羟基丁酸 (GHB) 。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
S Landaas et al.
Clinica chimica acta; international journal of clinical chemistry, 78(3), 489-493 (1977-08-01)
Examination of urine samples by capillary column gas chromatography and mass spectrometry showed the presence of 2-hydroxyisovaleric acid together with trace amounts of the three branched-chain 2-keto acids in five patients with lactic and ketoacidosis. None of these compounds was
F Magni et al.
Analytical biochemistry, 220(2), 308-314 (1994-08-01)
A sensitive method for the simultaneous analysis of plasma alpha-ketoisocaproic acid (KIC) and leucine using GC-MS is described. Plasma was deproteinized after addition of both alpha-ketovaleric acid and norleucine as internal standards. Derivatization of the compounds involved protection of the
Direct chiral resolution of aliphatic a-hydroxy acids using 2-hydroxypropyl-?-cyclodextrin in capillary electrophoresis.
Kodama S, et al.
Analyst, 124(1), 55-59 (1999)
Y M Pan et al.
Journal of analytical toxicology, 25(5), 328-332 (2001-08-14)
The modification of a procedure originally developed for the analysis of ethylene glycol (EG) in serum was also found to permit the simultaneous analysis of gamma-hydroxybutyrate (GHB) in whole blood. The primary feature of the EG procedure was that it
Biotinidase deficiency: metabolites in CSF.
A Fois et al.
Journal of inherited metabolic disease, 9(3), 284-285 (1986-01-01)
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