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Merck
CN

219630

Sigma-Aldrich

DL-2,3-二胺基丙酸 单盐酸盐

98%

别名:

3-氨基-DL-丙氨酸 单盐酸盐

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About This Item

线性分子式:
NH2CH2CH(NH2)COOH · HCl
CAS号:
分子量:
140.57
Beilstein:
5293359
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

solid

反应适用性

reaction type: solution phase peptide synthesis

mp

232 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

Cl[H].NCC(N)C(O)=O

InChI

1S/C3H8N2O2.ClH/c4-1-2(5)3(6)7;/h2H,1,4-5H2,(H,6,7);1H

InChI key

SKWCZPYWFRTSDD-UHFFFAOYSA-N

一般描述

DL-2,3-Diaminopropionic acid monohydrochloride also known as 3-Amino-DL-alanine monohydrochloride, is commonly used in solution phase peptide synthesis.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lauren B Retzloff et al.
Anticancer research, 30(1), 19-30 (2010-02-13)
Gastrin-releasing peptide (GRP) receptors are overexpressed on a variety of human carcinomas, including those of the breast. These receptors may be targeted with bombesin (BBN), which binds to GRP receptors with high affinity and specificity. The aim of this study
Fumiko Fujisaki et al.
Chemical & pharmaceutical bulletin, 52(10), 1238-1241 (2004-10-07)
A conventional new route to the novel oxazolidin-2-one derivatives (3a-f) having two substituents on N-3 and C-4 in the oxazolidin-2-one ring was established with racemic beta-aminoalanine derivatives (1) as the key starting materials.
Min Zhong et al.
Bioorganic & medicinal chemistry letters, 21(1), 307-310 (2010-11-27)
This letter describes the structure-activity relationship (SAR) of the 'right-wing' α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. Novel (S)-substituted heteroaryl-bearing α-amino acids have been identified as replacements of the 'right-wing' (S)-2,3-diaminopropanoic acid (DAP) moiety. Improvement of potency in
Marek Cebecauer et al.
Journal of immunology (Baltimore, Md. : 1950), 174(11), 6809-6819 (2005-05-21)
Soluble MHC-peptide (pMHC) complexes, commonly referred to as tetramers, are widely used to enumerate and to isolate Ag-specific CD8(+) CTL. It has been noted that such complexes, as well as microsphere- or cell-associated pMHC molecules compromise the functional integrity of
Huan-Huan Zhang et al.
The Journal of organic chemistry, 73(9), 3634-3637 (2008-03-28)
A novel and convenient route to the asymmetric synthesis of 2,3-diamino acids via Mannich reaction of iminolactones 1a and 1b with N-protected imines has been achieved in good yields (up to 95%) and high diastereoselectivity (dr: >99:1). Hydrolysis of the

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