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方案
98%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
应用
peptide synthesis
SMILES字符串
NC1(CCCCC1)C(O)=O
InChI
1S/C7H13NO2/c8-7(6(9)10)4-2-1-3-5-7/h1-5,8H2,(H,9,10)
InChI key
WOXWUZCRWJWTRT-UHFFFAOYSA-N
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
B Jastrzebska et al.
The journal of peptide research : official journal of the American Peptide Society, 62(2), 70-77 (2003-06-26)
In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic acid (Acc). All peptides were tested for the pressor, antidiuretic and uterotonic in
Francisco Rodríguez-Ropero et al.
Journal of chemical information and modeling, 48(2), 333-343 (2008-01-19)
Conformationally restricted amino acids are promising candidates to serve as basic pieces in redesigned protein motifs which constitute the basic modules in synthetic nanoconstructs. Here we study the ability of constrained cyclic amino acid 1-aminocyclohexane-1-carboxylic acid (Ac6c) to stabilize highly
Nicolas Fabresse et al.
Journal of pharmaceutical and biomedical analysis, 141, 149-156 (2017-04-27)
Tranexamic acid is a widely used antifibrinolytic drug but its pharmacology and pharmacokinetics remains poorly understood. Owing to the recent knowledge on phospholipid-induced matrix effects during human plasma analysis, our aim was to develop a liquid chromatography-mass spectrometry method for
M Sukumar et al.
Biochemical and biophysical research communications, 128(1), 339-344 (1985-04-16)
Analogs of chemotactic peptides (Formyl-Met-X-Phe-OMe) containing the stereochemically constrained residues alpha-aminoisobutyric acid (Aib), 1-aminocyclopentanecarboxylic acid (Acc5) and 1-aminocyclohexanecarboxylic acid (Acc6) at position 2 are compared with the parent sequence (X = Leu) for their ability to induce lysozyme release in
Olga Labudda et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(12), 775-779 (2006-11-30)
A sterically constrained non-coded amino acid, 1-aminocyclopentane-1-carboxylic acid (Apc), was introduced in position 7 or 8 of the bradykinin (BK) B(2) receptor antagonist, [D-Arg(0), Hyp(3), Thi(5, 8), D-Phe(7)]BK, previously synthesized by Stewart's group. This modification is believed to reduce the
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