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质量水平
方案
97%
mp
>300 °C (lit.)
官能团
carboxylic acid
SMILES字符串
Nc1ccc(cn1)C(O)=O
InChI
1S/C6H6N2O2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H2,7,8)(H,9,10)
InChI key
ZCIFWRHIEBXBOY-UHFFFAOYSA-N
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一般描述
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.
应用
6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Raman Sharma et al.
Xenobiotica; the fate of foreign compounds in biological systems, 49(12), 1447-1457 (2019-02-13)
1. The absorption, metabolism, and excretion of a single oral 450-mg dose of [14C]-(S)-6-(3-cyclopentyl-2-(4-trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid (PF-04991532), a hepatoselective glucokinase activator, was investigated in humans. Mass balance was achieved with ∼94.6% of the administered dose recovered in urine and feces. The
A three-component solid-phase synthesis of 3-aminoimidazo [1, 2-a] azines.
Blackburn C.
Tetrahedron Letters, 39(31), 5469-5472 (1998)
J W Foster et al.
Journal of general microbiology, 130(11), 2873-2881 (1984-11-01)
Mutants of Salmonella typhimurium supersensitive to the nicotinic acid analogue 6-amino-nicotinic acid (6ANA) were isolated as unable to grow on what are normally subinhibitory concentrations of the analogue. The mutations were classified on the basis of their map positions as
D J Jamieson et al.
Journal of bacteriology, 168(1), 389-397 (1986-10-01)
Expression of the tripeptide permease gene tppB is anaerobically induced. This induction is independent of the fnr (oxrA) gene product, which is known to be required for the anaerobic induction of several respiratory enzymes. We isolated, characterized, and mapped mutations
Electrocatalytic synthesis of 6-aminonicotinic acid at silver cathodes under mild conditions.
Gennaro A, et al.
Electrochemical Communications, 6(7), 627-631 (2004)
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