211370
磺酰胺
99%
别名:
磺酰二胺, 磺酰胺, 酰亚胺氨基磺酸
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关于此项目
线性分子式:
(NH2)2SO2
化学文摘社编号:
分子量:
96.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
232-262-9
MDL number:
Assay:
99%
General description
磺酰胺，一种与格氏试剂相容的极性非质子溶剂，可用作医学化学中的官能团。
Application
磺胺被用于合成以下物质：
- ArCH=NSO2NH2型席夫碱
- 1H,3H-2,1,3-苯并噻二嗪-4-酮-2,2-二氧化物（BTDD）
- 在一项PPARα激活的研究中，合成油酰乙醇胺类似物的磺酰胺类似物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Anna Di Fiore et al.
Bioorganic & medicinal chemistry letters, 20(12), 3601-3605 (2010-05-18)
We investigated the inhibition of carbonic anhydrase (CA, EC 4.2.1.1) isoforms I-XV with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfamide and other simple or sugar sulfamides, a class of less investigated CA inhibitors (CAIs). The crystal structure of the adduct of hCA II with the boron-substituted
Anomeric effects in sulfamides
Eric H et al.
The Journal of Physical Chemistry A, 120, 3677-3682 (2016)
Sulfamides and sulfonamides as polar aprotic solvents
Herman R G et al.
The Journal of Organic Chemistry, 52, 479-483 (1987)
Bacterial cleavage of nitrogen to sulfone bonds in sulfamide and 1H-2, 1, 3-benzothiadiazin-4 (3H)-one 2, 2-dioxide: formation of 2-nitrobenzamide by Gordonia sp.
Rein U and Cook AM.
FEMS Microbiology Letters, 172(2), 107-113 (1999)
Anthony Bertucci et al.
Bioorganic & medicinal chemistry letters, 19(3), 650-653 (2009-01-06)
The inhibition of a coral carbonic anhydrase (CA, EC 4.2.1.1) has been investigated with a series of inorganic anions such as halogenides, pseudohalogenides, bicarbonate, carbonate, nitrate, nitrite, hydrogen sulfide, bisulfite, perchlorate, sulfate. The full-length scleractinian coral Stylophora pistillata CA, STPCA
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