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Merck
CN

210218

Sigma-Aldrich

3-二甲氨基-1,2-丙二醇

98%

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别名:
(±)-3-(Dimethylamino)-1,2-propanediol, 1,2-Dihydroxy-3-(dimethylamino)propane, Methicol
线性分子式:
(CH3)2NCH2CH(OH)CH2OH
CAS号:
分子量:
119.16
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

折射率

n20/D 1.4609 (lit.)

bp

216-217 °C (lit.)

密度

1.004 g/mL at 25 °C (lit.)

SMILES字符串

CN(C)CC(O)CO

InChI

1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3

InChI key

QCMHUGYTOGXZIW-UHFFFAOYSA-N

应用

3-二甲胺基-1,2-丙二醇可用于制备:
  • 合成阳离子脂质,N-[1-(2,3-二油氧基)丙基-N,N,N-三甲基氯化铵(DOTMA),用于DNA转染方案
  • 茚满衍生的噁唑啉

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

221.0 °F

闪点(°C)

105 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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An efficient synthesis of indane-derived bis (oxazoline) and its application to hetero Diels-Alder reactions on polymer support.
Kurosu M, et al.
Tetrahedron Letters, 45(1), 145-148 (2004)
P L Felgner et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(21), 7413-7417 (1987-11-01)
A DNA-transfection protocol has been developed that makes use of a synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA). Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of the DNA, DOTMA facilitates fusion of
Shuo Fang et al.
International journal of pharmaceutics, 493(1-2), 460-465 (2015-08-11)
A novel dual drug-tailed betaine conjugate amphiphile has been firstly synthesized in which the polar headgroup is derived from glycine betaine and the hydrophobic tails are chlorambucil molecules. The newly prepared conjugate undergoes self-assembly to form stable liposome-like nanocapsules as

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