跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

210145

Sigma-Aldrich

2,2-二甲基-1,3-二噁烷-4,6-二酮

98%

别名:

丙二酸亚异丙酯, 丙二酸环亚异丙酯, 米氏酸

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C6H8O4
CAS号:
2033-24-1
分子量:
144.13
Beilstein:
117310
EC 号:
217-992-8
MDL编号:
MFCD00006638
UNSPSC代码:
12352100
PubChem化学物质编号:
24852618
NACRES:
NA.22

质量水平

200

方案

98%

表单

solid

mp

92-96 °C (lit.)

溶解性

dioxane: soluble 5%, clear to very slightly hazy, colorless to faintly yellow

官能团

ester
ketal

储存温度

2-8°C

SMILES字符串

CC1(C)OC(=O)CC(=O)O1

InChI

1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3

InChI key

GXHFUVWIGNLZSC-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

2,2-二甲基-1,3-二恶烷-4,6-二酮（米氏′酸）广泛用于有机合成，特别是对于多种CC键形成，因为它具有足够的酸性 (pKa 4.83) 和空间刚性。醛与米氏′酸之间的Knoevenagel缩合反应在离子液体中加速。

米氏′酸被用作合成杂环的有价值的起始原料和有机合成反应的中间体。

应用

2,2-二甲基-1,3-二恶烷-4,6-二酮用于合成：
  • 大环 β-酮内酯
  • 4-吡啶基取代的杂环
  • 2-取代吲哚
  • 异秦皮啶。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCH9274
STBJ3104
STBF4868V
STBG8233
STBD6952V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

New multicomponent domino reactions (MDRs) in water: highly chemo-, regio-and stereoselective synthesis of spiro {[1, 3] dioxanopyridine}-4, 6-diones and pyrazolo [3, 4-b] pyridines.
Ma N, et al.
Green Chemistry, 12?(8), 1357-1361 (2010)
Davood Nematollahi et al.
Chemical & pharmaceutical bulletin, 58(1), 23-26 (2010-01-05)
Electrochemical oxidation of catechols in the presence of phenyl-Meldrum's acid as a nucleophile in aqueous solution has been studied in detail by means of cyclic voltammetry and controlled potential coulometry. The results indicate that the o-benzoquinone derived from catechols participates
The synthesis of β-keto lactones via cyclization of β-keto ester dianions or the cyclization of Meldrum's acid derivatives.
Lermer L, et al.
Canadian Journal of Chemistry, 70(5), 1427-1445 (1992)
Songlei Zhu et al.
Molecules (Basel, Switzerland), 17(12), 13856-13863 (2012-11-24)
A series of 4-aryl-6-methyl-3,4-dihydro-2H-pyrano[3,2-c]quinolin-2,5(6H)-diones were synthesized via the three-component reactions of aromatic aldehydes, 4-hydroxy-1-methylquinolin-2(1H)-one, and Meldrum's acid catalyzed by L-proline. The structures of the products were identified by spectroscopic analysis. A mechanism for this three-component reaction catalyzed by L-proline was
C, O-Dialkylation of Meldrum's Acid: Synthesis and Reactivity of 1, 3, 7, 7-Tetramethyl-4 H, 10 H-6, 8, 9-trioxa-2-thiabenz [f] azulen-5-one
Snyder CA, et al.
The Journal of Organic Chemistry, 68(19), 7455-7459 (2013)
查看所有相关文献

商品

Knoevenagel Condensation Reaction

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门