205494
二丁基二氯化锡
96%
别名:
二丁基二氯锡
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关于此项目
线性分子式:
(CH3CH2CH2CH2)2SnCl2
化学文摘社编号:
分子量:
303.84
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-670-0
Beilstein/REAXYS Number:
3535484
MDL number:
产品名称
二丁基二氯化锡, 96%
InChI key
RJGHQTVXGKYATR-UHFFFAOYSA-L
InChI
1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2
SMILES string
CCCC[Sn](Cl)(Cl)CCCC
assay
96%
form
solid
bp
135 °C/10 mmHg (lit.)
mp
37-40 °C (lit.)
Quality Level
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Application
- 二丁基锡化合物对PPARγ/RXRα活性的影响：研究包括二氯化二丁基锡在内的各种二丁基锡化合物对哺乳动物细胞脂肪生成和炎症的影响，强调其对PPARγ/RXRα通路的影响（Milton et al., 2017）。
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Oral - STOT SE 1 Oral
target_organs
thymus
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Synthetic Communications, 12, 495-495 (1982)
Louis P Vera-Portocarrero et al.
Gastroenterology, 135(4), 1369-1378 (2008-08-13)
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Kent J Fanning et al.
Antimicrobial agents and chemotherapy, 55(6), 3008-3011 (2011-03-16)
This work sought to define how pancreatitis affected antibiotic distribution in a perfused rat pancreas model. The distribution kinetics of four antibiotics were examined in control animals and animals with pancreatitis. Meropenem and piperacillin distributed into the extracellular space, and
Gisela Sparmann et al.
Cell research, 20(3), 288-298 (2010-01-27)
Origin and fate of pancreatic stellate cells (PSCs) before, during and after pancreatic injury are a matter of debate. The crucial role of PSCs in the pathogenesis of pancreatic fibrosis is generally accepted. However, the turnover of the cells remains
Toyoma Kaku et al.
Pancreas, 34(3), 299-309 (2007-04-07)
Chronic pancreatitis consists of excessive leukocyte infiltration and fibrosis. IS-741 has been reported to be an antiinflammatory drug through an inhibitory action on cell adhesion. In this study, we investigated whether IS-741 could inhibit the progression of pancreatic fibrosis through
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