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质量水平
方案
99.995% trace metals basis
表单
powder
反应适用性
core: arsenic
reagent type: catalyst
SMILES字符串
O=[As]O[As]=O
InChI
1S/As2O3/c3-1-5-2-4
InChI key
IKWTVSLWAPBBKU-UHFFFAOYSA-N
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一般描述
氧化砷(ATO)是一种无机形式的砷,可用作治疗急性早幼粒细胞白血病(APL)患者的治疗化合物。目前正在开发许多药物传递方法,利用纳米技术克服由于快速从血液中清除而导致生物利用度差的问题。
应用
- 电化学检测应用:一项关于包含功能化碳纳米纤维的镧基钙钛矿的研究强调了三氧化二砷在水和食品样品中洛克沙砷(roxarsone)电化学检测的用途,提供了一种提高安全性和环境监测方法 (John Felix MA et al., 2024)。
- 癌症研究中的抗增殖作用:该研究显示了三氧化二砷与二甲双胍联用对KG1a细胞增殖的抑制作用,表明其在抗肿瘤策略制定方面的潜在效用(Huang-Li WH et al., 2024)。
- 环境修复:这篇关于氧化锰基除砷材料的综述讨论了三氧化二砷在环境修复中的应用,重点介绍了砷净化技术的有效性和进展 (Younas M et al., 2024)。
警示用语:
Danger
危险分类
Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1
靶器官
Respiratory system,Cardio-vascular system,Gastrointestinal tract
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
A facile route to core?shell nanoparticulate formation of arsenic trioxide for effective solid tumor treatment.
Zhang Z, et al.
Nanoscale, 8(7), 4373-4380 (2016)
Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers.
Akhtar A, et al.
Journal of biomedical research, 31(3), 177-177 (2017)
Silica nanovehicles endow arsenic trioxide with an ability to effectively treat cancer cells and solid tumors.
Zhao Z, et al.
Journal of Materials Chemistry, 2(37), 6313-6323 (2014)
Ruoshi Xu et al.
Bone research, 6, 33-33 (2018-11-28)
How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
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