199338
1,4-二氨基-2-丁酮 二盐酸盐
99%
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关于此项目
线性分子式:
H2NCH2CH2COCH2NH2 · 2HCl
化学文摘社编号:
分子量:
175.06
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-914-0
MDL number:
Assay:
99%
InChI key
HDRKYQXFDHZZOW-UHFFFAOYSA-N
InChI
1S/C4H10N2O.2ClH/c5-2-1-4(7)3-6;;/h1-3,5-6H2;2*1H
SMILES string
Cl[H].Cl[H].NCCC(=O)CN
assay
99%
mp
221 °C (dec.) (lit.)
functional group
amine, ketone
Application
1,4-Diamino-2-butanone dihydrochloride was used as a media supplement for the growth of B.pertussis and B. bronchiseptica.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A G Tkachenko et al.
Mikrobiologiia, 70(4), 487-494 (2001-09-18)
The level of expression of oxyR, the gene that protects Escherichia coli against oxidative stress, was enhanced by physiological concentrations of the biogenic amine putrescine. This level was directly proportional to the degree of negative DNA supercoiling. 1,4-Diamino-2-butanone (DAB), a
A G Tkachenko et al.
Biochemistry. Biokhimiia, 72(1), 109-116 (2007-02-21)
Mechanisms of antioxidant effect of polyamines were studied in dependence on the strength of superoxide stress. Under conditions of weak stress, polyamines from Escherichia coli cultures were shown to function mainly as a scavenger of free superoxide radicals, whereas under
T J Brickman et al.
Journal of bacteriology, 178(1), 54-60 (1996-01-01)
Chromosomal insertions defining Bordetella bronchiseptica siderophore phenotypic complementation group III mutants BRM3 and BRM5 were found to reside approximately 200 to 300 bp apart by restriction mapping of cloned genomic regions associated with the insertion markers. DNA hybridization analysis using
Yukihiro Ueno et al.
Biological & pharmaceutical bulletin, 27(6), 890-892 (2004-06-10)
Candida albicans generally grows in hyphae form in RPMI1640 medium. However, addition of 1,4-diamino-2-butanone (DAB), a competitive inhibitor of ornithine decarboxylase, decreased the amount of polyamines in C. albicans, and induced the proliferation of the C. albicans yeast form. The
D Menezes et al.
Parasitology research, 98(2), 99-105 (2005-11-12)
Trypanosoma cruzi is the etiological agent of American trypanosomiasis. Most of the available data on trypanosomatid parasites were obtained from African trypanosomes. Parasitic protozoa polyamine metabolism and transport pathways comprise valuable targets for chemotherapy. T. cruzi cannot synthesize putrescine, but
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