所有图片(4)
About This Item
经验公式（希尔记法）:
C12H6NNaO4
CAS号:
分子量:
251.17
Beilstein:
3794971
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
等级
certified by the Biological Stain Commission
质量水平
形式
powder
组成
Dye content, 75%
溶解性
1 M NH4OH: 1 mg/mL
λmax
380 nm (2nd)
598 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Na+].[O-]c1ccc2c(OC3=CC(=O)C=CC3=[N+]2[O-])c1
InChI
1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1
InChI key
IVGPGQSSDLDOLH-UHFFFAOYSA-M
正在寻找类似产品? 访问 产品对比指南
一般描述
刃天青(Resazurin)是二羟基吩噁嗪酮的N-氧化小分子衍生物。它是一种非离子染料，含有小的平面发色团。它是一种氧化还原指示剂，反应时由蓝紫色变为粉红色再变为无色。它也可用作3.5-6.5范围的pH指示剂，颜色由橙色变为蓝紫色。它的商品化形式为刃天青钠盐，也称3H-吩恶嗪-3-酮, 7-羟基-, 10-氧化物钠盐。经还原作用形成红色荧光的试卤灵（羟基吩噁嗪酮），进一步还原形成无色的氢化试卤灵。
应用
刃天青最常用作生物氧化还原指示剂。染料的生物还原减少了其氧化形式（蓝色）的含量，同时增加了荧光中间体（红色）水平。其应用包括：
- 测定酶活力和活细胞的增殖
- 检测乳汁中的细菌还原作用
- 在活力测定中用作检测活细菌的培养基成分
- 测定绵羊精液中活动精子的数目
- 检测乳酸脱氢酶
- 作为定量测定L-谷氨酸盐的分析试剂
用于测量活细胞的代谢活性和增殖。染料的生物还原减少了其氧化形式（蓝色）的含量，同时增加了荧光中间体（红色）水平。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Amir Kumar Singh et al.
Nature communications, 9(1), 4515-4515 (2018-10-31)
Dysregulated ROR-γt-mediated IL-17 transcription is central to the pathogenesis of several inflammatory disorders, yet the molecular mechanisms that govern the transcription factor activity of ROR-γt in the regulation of IL-17 are not fully defined. Here we show that SUMO-conjugating enzyme
Morris E Feldman et al.
PLoS biology, 7(2), e38-e38 (2009-02-13)
The mammalian target of rapamycin (mTOR) regulates cell growth and survival by integrating nutrient and hormonal signals. These signaling functions are distributed between at least two distinct mTOR protein complexes: mTORC1 and mTORC2. mTORC1 is sensitive to the selective inhibitor
Wen-Hao Guo et al.
Nature communications, 11(1), 4268-4268 (2020-08-28)
Current efforts in the proteolysis targeting chimera (PROTAC) field mostly focus on choosing an appropriate E3 ligase for the target protein, improving the binding affinities towards the target protein and the E3 ligase, and optimizing the PROTAC linker. However, due
Conn?s Biological Stains: A Handbook of Dyes, Stains and Fluorochromes for Use in Biology and Medicine (10th ed.)
R. W. Horobin and J. A. Kiernan (Eds.)
Conn?s Biological Stains (2002)
Andrej Wagner et al.
International journal of molecular sciences, 15(11), 20134-20157 (2014-11-08)
Photodynamic therapy (PDT) is a palliative treatment option for unresectable hilar biliary tract cancer (BTC) showing a considerable benefit for survival and quality of life with few side effects. Currently, factors determining the cellular response of BTC cells towards PDT
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门