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Merck
CN

197173

Sigma-Aldrich

2-肼-2-咪唑啉 氢溴酸盐

98%

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别名:
2-Hydrazino-4,5-dihydroimidazole hydrobromide
经验公式(希尔记法):
C3H8N4 · HBr
CAS号:
分子量:
181.03
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

mp

185-187 °C (lit.)

SMILES字符串

Br.NNC1=NCCN1

InChI

1S/C3H8N4.BrH/c4-7-3-5-1-2-6-3;/h1-2,4H2,(H2,5,6,7);1H

InChI key

HIJRJVVSABWXKG-UHFFFAOYSA-N

应用

2-Hydrazino-2-imidazoline hydrobromide was used in synthesis of:
  • some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
  • 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones, potential inodilating agents
Reactant for synthesis of:
  • Molecules that affect vasodilatory activity
  • Sulfate-bridges dimerica copper(II) complexes
  • 5-HT6 serotonin receptor antagonists
  • Pd complexes
  • Antidiabetic/antiobesity agents
  • DNA binders

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Dinesh Kumar et al.
Acta pharmaceutica (Zagreb, Croatia), 58(4), 393-405 (2008-12-24)
The present study describes the synthesis and pharmacological evaluation of 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones as potent inodilating agents. The synthesis of target compounds 2-4 and 7-11 was achieved by Friedel-Crafts acylation of appropriate anilide derivative with succinic anhydride or methylsuccinic anhydride and subsequent
Ranju Bansal et al.
European journal of medicinal chemistry, 44(11), 4441-4447 (2009-07-11)
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone are reported. An effect of substitution at 2-position of pyridazinone ring on vasodilatory potential has also been explored. The most active compound 6-[4-(2-oxo-2-pyrrolidin-1-yl-ethoxy)phenyl]-2-(4-fluorophenyl)-4,5-dihydropyridazin-3(2H)-one (11) exhibited vasodilating activity in nanomolar range
Mohamed A Hashem et al.
Carbohydrate polymers, 237, 116177-116177 (2020-04-04)
A new hydrazono-imidazoline modified cellulose (HIMC) was synthesized for selective recovery of Pt(IV), Pd(II) and Au(III) from geological samples. Cellulose was oxidized by periodate and was further functionalized with hydrazono-imidazoline moieties to afford N-donor chelating fibers. Scanning electron microscopy (SEM)

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