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质量水平
方案
98%
表单
solid
mp
287 °C (dec.) (lit.)
官能团
nitro
SMILES字符串
[O-][N+](=O)c1ncc[nH]1
InChI
1S/C3H3N3O2/c7-6(8)3-4-1-2-5-3/h1-2H,(H,4,5)
InChI key
YZEUHQHUFTYLPH-UHFFFAOYSA-N
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一般描述
2-硝基咪唑是一种天然抗生素。
应用
2-硝基咪唑用于合成：
- 2-（2-硝基-1H-咪唑-1-基）乙基氨基甲酸叔丁酯
- 1-（2-（叔丁基二甲硅烷氧基）乙基）-2-硝基-1H-咪唑
- 2-氟-N-（2-（2-硝基-1H-咪唑-1-基）乙基）乙酰胺
- 2-（2-甲基-5-硝基-1H-咪唑-1H-基）乙基-2-氟乙酸酯
- 放射性标记前体 - 溴取代的类似物
- 硝基咪唑取代的硼酸，缺氧组织成像的前体
- 富含雌激素受体的肿瘤的潜在位点选择性放射增敏剂
包装
无底玻璃瓶。内含物装在插入的融合锥内。
分析说明
溶解度：
50 mg/mL，NH4OH：可溶、澄清、黄绿色至深黄绿色至深黄色
50 mg/mL，NH4OH：可溶、澄清、黄绿色至深黄绿色至深黄色
相关产品
产品编号
说明
价格
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Tetrahedron, 48, 10233-10233 (1992)
Zhihao Zha et al.
Nuclear medicine and biology, 38(4), 501-508 (2011-05-03)
Nitroimidazole (azomycin) derivatives labeled with radioisotopes have been developed as cancer imaging and radiotherapeutic agents based on the oncological hypoxic mechanism. By attaching nitroimidazole core with different functional groups, we synthesized new nitroimidazole derivatives and evaluated their potentiality as tumor
R K Jackson et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 31(5), 290-302 (2019-03-12)
The role of hypoxia in radiation resistance is well established and many approaches to overcome hypoxia in tumours have been explored, with variable success. Two small molecule strategies for targeting hypoxia have dominated preclinical and clinical efforts. One approach has
J. Chem. Res. Synop., 92-92 (1993)
Kazuki Yoshihara et al.
Chembiochem : a European journal of chemical biology, 18(16), 1650-1658 (2017-05-16)
The use of DNA aggregates could be a promising strategy for the molecular imaging of biological functions. Herein, phosphorescent oligodeoxynucleotides were designed with the aim of visualizing oxygen fluctuation in tumor cells. DNA-ruthenium conjugates (DRCs) that consisted of oligodeoxynucleotides, a
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