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Merck
CN

195413

甲基丙烯腈

99%

别名:

1-Methylethenyl cyanide, 2-Cyano-1-propene, 2-Methyl-2-propenenitrile, 2-Methylpropenenitrile, Isobutenenitrile, Isopropene cyanide, Methacrylnitrile

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关于此项目

线性分子式:
CH2=C(CH3)CN
化学文摘社编号:
分子量:
67.09
EC Number:
204-817-5
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
773708
MDL number:
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产品名称

甲基丙烯腈, 99%

InChI key

GYCMBHHDWRMZGG-UHFFFAOYSA-N

InChI

1S/C4H5N/c1-4(2)3-5/h1H2,2H3

SMILES string

CC(=C)C#N

vapor pressure

64 mmHg ( 20 °C)

assay

99%

contains

50 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.400 (lit.)

bp

90-92 °C (lit.)

mp

−35.8 °C (lit.)

density

0.8 g/mL at 25 °C (lit.)

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signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Flam. Liq. 2 - Skin Sens. 1 - STOT SE 1

target_organs

Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

53.6 °F - closed cup

flash_point_c

12 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Birgit Grill et al.
Molecules (Basel, Switzerland), 25(11) (2020-06-03)
Nitrile hydratases (NHase) catalyze the hydration of nitriles to the corresponding amides. We report on the heterologous expression of various nitrile hydratases. Some of these enzymes have been investigated by others and us before, but sixteen target proteins represent novel
T Samikkannu et al.
Toxicology letters, 92(1), 15-20 (1997-06-16)
The effect of methacrylonitrile (MeAN) a cyanogen compound, on various haematological parameters was studied. Administration of MeAN at 100 mg/kg per body weight/day for 7 days resulted in a significant decrease in the red cell count and in the level
National Toxicology Program technical report series, (497)(497), 1-225 (2002-01-24)
Methacrylonitrile is an unsaturated aliphatic nitrile. It is widely used in the preparation of homopolymers and copolymers, elastomers, and plastics and as a chemical intermediate in the preparation of acids, amides, amines, esters, and other nitriles. Methacrylonitrile is also used
V Vasanthakumari et al.
Indian journal of biochemistry & biophysics, 34(6), 540-542 (1998-05-22)
MeAN administration (40mg/kg body wt/day (i.e. 1/5 of LD50) resulted in increased levels of lipid peroxidation products, conjugated dienes and lipofuscin-like substances in rat liver. Significant decrease in GSH and a decreased activity of hepatic SOD, CAT and GPx were
Hongbing Wang et al.
Journal of toxicology and environmental health. Part A, 65(7), 523-537 (2002-04-10)
Tissue-specific induction of cytochrome P-450s (CYP) followed by increased in situ bioactivation may contribute to chemical-induced site-specific toxicity. In rats, methacrylonitrile (MAN) is metabolized by cytochrome P-450 2E1 (CYP2E1) to acetone, which is eliminated along with parent MAN in breath.

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