质量水平
检测方案
99%
形式
liquid
折射率
n20/D 1.524 (lit.)
bp
133-134 °C (lit.)
密度
1.09 g/mL at 25 °C (lit.)
SMILES字符串
Cc1cscn1
InChI
1S/C4H5NS/c1-4-2-6-3-5-4/h2-3H,1H3
InChI key
QMHIMXFNBOYPND-UHFFFAOYSA-N
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一般描述
4-甲基噻唑与钴(II)、锌(II)、镍(II)和铜(II)卤化物形成络合物。
应用
4-甲基噻唑被用于合成催化的dendrophanes，作为硫胺二磷酸依赖性酶丙酮酸氧化酶的功能模拟物。它被用于3-丁基-4-甲基噻唑鎓溴化物的小规模制备。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Sarah E O'Connor et al.
Biochemistry, 41(17), 5685-5694 (2002-04-24)
The biosynthesis of epothilones, a family of hybrid polyketide (PK)/nonribosomal peptide (NRP) antitumor agents, provides an ideal system to study a hybrid PK/NRP natural product with significant biomedical value. Here the third enzyme involved in epothilone production, the five domain
Shivaji H Shelke et al.
Bioorganic & medicinal chemistry letters, 22(20), 6373-6376 (2012-09-18)
A new series of 3-aryl-2-(2-aryl/benzyl-4-methylthiazole-5-yl)thiazolidin-4-one was synthesized by condensation of 2-aryl/benzyl-4-methylthiazole-5-carbaldehyde, aromatic amines and thioglycolic acid in toluene. All the synthesized compounds are characterized by IR, NMR and elemental or mass analysis. Sixteen out of the newly synthesized compounds were
Improved preparations of ionic liquids using microwave irradiation.
Deetlefs M and Seddon KR.
Green Chemistry, 5(2), 181-186 (2003)
Metal complexes of 4-methylthiazole.
Hughes MN and Rutt KJ.
Inorganic Chemistry, 10(2), 414-416 (1971)
Catalytic Dendrophanes as Enzyme Mimics: Synthesis, Binding Properties, Micropolarity Effect, and Catalytic Activity of Dendritic Thiazolio-cyclophanes.
Habicher T, et al.
Helvetica Chimica Acta, 82(7), 1066-1095 (1999)
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