产品名称
4-甲基噻唑, 99%
InChI key
QMHIMXFNBOYPND-UHFFFAOYSA-N
InChI
1S/C4H5NS/c1-4-2-6-3-5-4/h2-3H,1H3
SMILES string
Cc1cscn1
assay
99%
form
liquid
refractive index
n20/D 1.524 (lit.)
bp
133-134 °C (lit.)
density
1.09 g/mL at 25 °C (lit.)
Quality Level
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Application
4-甲基噻唑被用于合成催化的dendrophanes，作为硫胺二磷酸依赖性酶丙酮酸氧化酶的功能模拟物。它被用于3-丁基-4-甲基噻唑鎓溴化物的小规模制备。
General description
4-甲基噻唑与钴(II)、锌(II)、镍(II)和铜(II)卤化物形成络合物。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
89.6 °F - closed cup
flash_point_c
32 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Improved preparations of ionic liquids using microwave irradiation.
Deetlefs M and Seddon KR.
Green Chemistry, 5(2), 181-186 (2003)
Metal complexes of 4-methylthiazole.
Hughes MN and Rutt KJ.
Inorganic Chemistry, 10(2), 414-416 (1971)
Catalytic Dendrophanes as Enzyme Mimics: Synthesis, Binding Properties, Micropolarity Effect, and Catalytic Activity of Dendritic Thiazolio-cyclophanes.
Habicher T, et al.
Helvetica Chimica Acta, 82(7), 1066-1095 (1999)
M K Cho et al.
Toxicology, 146(2-3), 111-122 (2000-05-18)
Microsomal epoxide hydrolase (mEH) is inducible by a number of xenobiotics. Induction of mEH by certain chemopreventive agents may implicate the protective effect. In contrast, many of carcinogenic agents also induce the enzyme. The hepatotoxicity and mEH expression by methylthiazoles
Sarah E O'Connor et al.
Biochemistry, 41(17), 5685-5694 (2002-04-24)
The biosynthesis of epothilones, a family of hybrid polyketide (PK)/nonribosomal peptide (NRP) antitumor agents, provides an ideal system to study a hybrid PK/NRP natural product with significant biomedical value. Here the third enzyme involved in epothilone production, the five domain
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