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Merck
CN

193526

Sigma-Aldrich

1,4-二碘苯

99%

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别名:
4-Iodophenyl iodide, p-Diiodobenzene, p-Phenylene diiodide
经验公式(希尔记法):
C6H4I2
CAS号:
分子量:
329.90
Beilstein:
1904546
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

powder

bp

285 °C (lit.)

mp

131-133 °C (lit.)

SMILES字符串

Ic1ccc(I)cc1

InChI

1S/C6H4I2/c7-5-1-2-6(8)4-3-5/h1-4H

InChI key

LFMWZTSOMGDDJU-UHFFFAOYSA-N

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应用

1,4-二碘苯用于:
  • 全合成马来酸,一种天然存在的缓激肽受体拮抗剂
  • 通过 Pd11/Cu1 催化交叉偶联反应制备 1,4-双(-R-苯基乙炔基)苯
  • 合成 1,4-二碘-2,5-二十二烷基苯,用于制备低聚(1,4-亚苯基亚乙炔基)的起始试剂
  • 表面介导的外延排列合成和通过 Ullmann 脱卤反应分离铜(110)上的聚苯系列

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Synthesis of symmetric and unsymmetric 1, 4-bis ( p-R-phenylethynyl) benzenes via palladium/copper catalyzed cross-coupling and comments on the coupling of aryl halides with terminal alkynes.
Nguyen P, et al.
Inorgorganica Chimica Acta, 220(1), 289-296 (1994)
Du Zong-Da et al.
Journal of chromatography. A, 1616, 460791-460791 (2019-12-24)
Microporous organic network (MON) is a promise class of functional materials in solid phase extraction (SPE). However, the previous MON-based SPE works are all focused on off-line mode. The inherent drawbacks of off-line SPE such as complicated operation steps and
Rapid bi-directional synthesis of oligo (1, 4-phenylene ethynylene) s.
Huang S and Tour JM.
Tetrahedron Letters, 40(17), 3447-3450 (1999)
D Ma et al.
Organic letters, 3(14), 2189-2191 (2001-07-07)
[reaction: see text] The first total synthesis of martinellic acid, a naturally occurring bradykinin receptor antagonist, via a CuI-catalyzed coupling reaction of beta-amino ester 6 with 1,4-diiodobenzene and a guanylation reaction of secondary amine 3 under mild conditions as key
Uta Funke et al.
Pharmaceuticals (Basel, Switzerland), 5(2), 169-188 (2012-01-01)
Phosphodiesterase 10A (PDE10A) is a key enzyme of intracellular signal transduction which is involved in the regulation of neurotransmission. The molecular imaging of PDE10A by PET is expected to allow a better understanding of physiological and pathological processes related to

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