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方案
97%
沸点
85-90 °C/10 mmHg (lit.)
mp
20 °C (lit.)
官能团
hydroxyl
SMILES字符串
NC1(CO)CCCC1
InChI
1S/C6H13NO/c7-6(5-8)3-1-2-4-6/h8H,1-5,7H2
InChI key
PDNZJLMPXLQDPL-UHFFFAOYSA-N
应用
1-Amino-1-cyclopentanemethanol was used in the synthesis of xanthine-derived heterocyclic fused systems. It was also used as building block in medicinal chemistry synthesis.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
204.8 °F - closed cup
闪点(°C)
96 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Journal of medicinal chemistry, 50(10), 2341-2351 (2007-04-24)
1-isoquinolinylguanidines were previously disclosed as potent and selective inhibitors of urokinase-type plasminogen activator (uPA). Further investigation of this template has revealed that incorporation of a 7-sulfonamide group furnishes a new series of potent and highly selective uPA inhibitors. Potency and
Methods for the synthesis of xanthine-derived polycyclic fused systems.
Heterocyclic Communications, 19(5), 297-310 (2013)
Journal of medicinal chemistry, 49(14), 4409-4424 (2006-07-11)
Female sexual arousal disorder (FSAD) is a highly prevalent sexual disorder affecting up to 40% of women. We describe herein our efforts to identify a selective neutral endopeptidase (NEP) inhibitor as a potential treatment for FSAD. The rationale for this
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