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描述
biological oxygen demand (BOD) 14,000 ppm
质量水平
形式
powder
自燃温度
752 °F
分子量
average Mw ~1,000,000
杂质
<5 wt. %
粒径
20 mesh (99% through)
pH值(酸碱度)
5.0-8.5
界面张力矿物油
12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)
粘度
1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)
溶解性
H2O: insoluble (above 45 °C)
polar organic solvents: soluble
密度
0.5 g/mL at 25 °C (lit.)
InChI
1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
InChI key
RRHXDYJWVYFMKV-UHFFFAOYSA-N
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应用
- 热响应性水性泡沫:研究人员已经研究了羟丙基纤维素作为绿色聚合物的性质,它可以随温度变化改变溶解性,适用于响应性泡沫应用 (Braunschweig, 2019)。
- 水溶液中的相互作用机制:一项有关溶液中羟丙基纤维素和水相互作用的研究,重点关注了聚合物链长在确定溶液物理性质中的重要性 (Martin-Pastor and Stoyanov, 2020)。
- 腐蚀抑制:研究显示了羟丙基纤维素作为酸性环境中铝腐蚀抑制剂的有效性,重点介绍了其在材料科学和工程应用中的潜力 (Jarkas et al., 2019)。
- 口腔崩解膜:该应用涉及羟丙基纤维素膜的配方设计,目的在于改善药物的递送和溶出曲线,它在药物递送和药物科学中有重要意义 (Takeuchi et al., 2018)。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of
Drug development and industrial pharmacy, 39(2), 290-298 (2012-04-25)
The objective of this study was to improve the dissolution rate and to enhance the stability of a poorly water-soluble and low glass-trasition temperature (T(g)) model drug, fenofibrate, in low molecular weight grades of hydroxypropylcellulose matrices produced by hot-melt extrusion
Chemical & pharmaceutical bulletin, 60(11), 1380-1386 (2012-11-06)
We evaluated models for predicting spray mist diameter suitable for scaling-up the fluidized bed granulation process. By precise selection of experimental conditions, we were able to identify a suitable prediction model that considers changes in binder solution, nozzle dimension, and
Journal of pharmaceutical sciences, 101(8), 2941-2951 (2012-05-26)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystallization technique has been widely applied to inorganic materials, although it has seldom been used with drugs. In this study
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
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