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质量水平
方案
98%
表单
powder
旋光性
[α]19/D +90°, c = 0.5 in KH2PO4/trace NaOH
反应适用性
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
抗生素抗菌谱
Gram-positive bacteria
应用
peptide synthesis
作用机制
cell wall synthesis | interferes
储存温度
2-8°C
SMILES字符串
[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2N)C(O)=O
InChI
1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
InChI key
HSHGZXNAXBPPDL-HZGVNTEJSA-N
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一般描述
化学结构:β-内酰胺
应用
7-氨基头孢烷酸(7-ACA)可用作制备以下物质的原料:
- 在三乙胺存在的情况下与 S-苯并噻唑-2-基(2-氨基-4-噻唑基)(甲氧基亚氨基)硫代乙酸酯 (MAEM)反应合成的头孢噻肟 。
- 通过头孢噻肟中间体合成的第三代抗生素头孢泊肟酯。
- 作为β-内酰胺酶潜在抑制剂的3′-取代头孢菌素钠砜衍生物。
细菌(金黄色葡萄球菌)β-内酰胺酶的有效抑制剂。
警示用语:
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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