190675
4-甲基-5-噻唑乙醇
98%
别名:
5-(2-羟乙基)-4-甲基噻唑, 磺酰醇
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关于此项目
经验公式（希尔记法）:
C6H9NOS
化学文摘社编号:
分子量:
143.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-272-6
Beilstein/REAXYS Number:
114249
MDL number:
Assay:
98%
Form:
liquid
refractive index
n20/D 1.550 (lit.)
bp
135 °C/7 mmHg (lit.)
solubility
alcohol: soluble(lit.), benzene: soluble(lit.), chloroform: soluble(lit.), diethyl ether/hexanes: soluble(lit.), water: very soluble(lit.)
density
1.196 g/mL at 25 °C (lit.)
functional group
hydroxyl
InChI key
BKAWJIRCKVUVED-UHFFFAOYSA-N
InChI
1S/C6H9NOS/c1-5-6(2-3-8)9-4-7-5/h4,8H,2-3H2,1H3
SMILES string
Cc1ncsc1CCO
assay
98%
form
liquid
Quality Level
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General description
4-Methyl-5-thiazoleethanol reacts with 4-ethyloctanoyl chloride to yield 4-methyl-5-thiazoleethanol 4-ethyloctanoate, sulfur-containing flavor compound. It was isolated from ether soluble alkaloidal fraction of Panax ginseng.
Application
4-Methyl-5-thiazoleethanol has been used in the synthesis of novel thiazolium halogenide ionic liquids.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
flash_point_f
233.6 °F - closed cup
flash_point_c
112 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Syntheses and Investigation of Properties of New Ionic Liquids Thiazolium Halogenide.
Wang QK, et al.
Advanced Materials Research, 332, 2036-2039 (2011)
A thiazole and two β-carboline constitutents from Panax ginseng.
Park JD, et al.
Archives of Pharmacal Research, 11(1), 52-55 (1988)
C Niederberger et al.
Gene, 171(1), 119-122 (1996-05-24)
Amiloride (Am) inhibits growth in the fission yeast Schizosaccharomyces pombe. We show that the toxic effect of this drug is relieved by low concentrations of thiamine (Th) and that the pyrimidine moiety of the Th molecule is responsible for growth
E Bellion et al.
Biochimica et biophysica acta, 735(3), 331-336 (1983-11-23)
The transport of thiamine and 4-methyl-5-hydroxyethylthiazole (MHET), its thiazole moiety, was studied using whole cells of Salmonella typhimurium. It was found that the bacteria possessed an active transport system for thiamine that had Km 0.21 microM and Vmax 33 nmol.min-1.(mg
Biosynthesis of thiamin thiazole: determination of the regiochemistry of the S/O acyl shift by using 1,4-dideoxy-D-xylulose-5-phosphate.
Abhishek Chatterjee et al.
Angewandte Chemie (International ed. in English), 45(21), 3507-3510 (2006-04-21)
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