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Merck
CN

190047

(-)-对溴四咪唑草酸盐

99%

别名:

(-)-4-溴四咪唑草酸盐, 6-Bromolevamisole oxalate, S(-)-6-(4-溴苯基)-2,3,5,6-四氢咪唑并[2,1-b]噻唑草酸盐

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关于此项目

经验公式（希尔记法）:
C11H11BrN2S · C2H2O4
化学文摘社编号:
62284-79-1
分子量:
373.22
UNSPSC Code:
12352200
NACRES:
NA.06
PubChem Substance ID:
24278147
EC Number:
263-487-0
Beilstein/REAXYS Number:
4944883
MDL number:
MFCD00070406
Assay:
99%
Form:
powder

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InChI key

ZULBIBHDIQCNIS-HNCPQSOCSA-N

InChI

1S/C11H11BrN2S.C2H2O4/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10;3-1(4)2(5)6/h1-4,10H,5-7H2;(H,3,4)(H,5,6)/t10-;/m1./s1

SMILES string

OC(=O)C(O)=O.Brc1ccc(cc1)[C@H]2CN3CCSC3=N2

assay

99%

form

powder

optical activity

[α]25/D −104°, c = 0.5 in H2O

mp

192 °C (dec.) (lit.)

functional group

bromo, carboxylic acid, thioether

Quality Level

100

相关类别

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCT2912
MKCS3812
MKCL4198
MKCH8427
MKCG1780

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R Béliveau et al.
The International journal of biochemistry, 20(4), 375-380 (1988-01-01)
1. Brush border membranes purified from rat kidney cortex were incubated in the presence of ATP and analysed by SDS polyacrylamide gel electrophoresis. 2. Quantitative analysis of phosphorylation was performed with a calibration curve obtained by autoradiography. 3. The presence
T Metaye et al.
Biochemical pharmacology, 37(22), 4263-4268 (1988-11-15)
Analogues of bromo-levamisole and guanidine derivatives including cimetidine are examined in vitro in order to investigate their comparative inhibition, towards alkaline phosphatase (ALP) from human liver and diamine-oxidase (DAO) from human placenta. Bromo-levamisole, considered as a potent selective uncompetitive inhibitor
J H Wöltgens et al.
Journal de biologie buccale, 13(1), 3-10 (1985-03-01)
This study was designed to compare the various phosphatases and pyrophosphatases in bone with those in developing teeth. Moreover the alkaline phosphatase inhibitor 1-p-bromotetramisole (1-pBTM) was assessed for its ability to discriminate between the several phosphatase activities. Enzyme activities were
J Luo et al.
American journal of physiology. Cell physiology, 279(1), C108-C119 (2000-07-18)
Genistein and bromotetramisole (Br-t) strongly activate cystic fibrosis transmembrane conductance regulator (CFTR; ABCC7) chloride channels on Chinese hamster ovary cells and human airway epithelial cells. We have examined the possible role of phosphatases in stimulation by these drugs using patch-clamp
T Metaye et al.
Biochemical pharmacology, 43(7), 1507-1511 (1992-04-01)
We studied the effect of bromolevamisole (BL) and other imidazo [2,1-b] thiazole derivatives--bromodexamisole (BD) and levamisole (LV)--on adenylate cyclase (AC) activity. BL and BD both inhibited forskolin-activated human thyroid AC, while LV had no effect. This inhibition was non-stereospecific and
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