推荐产品
方案
99%
mp
69-72 °C (lit.)
SMILES字符串
[O-][n+]1ccccc1S
InChI
1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,8H
InChI key
FGVVTMRZYROCTH-UHFFFAOYSA-N
相关类别
一般描述
2-巯基吡啶 N 氧化物与氯化钯反应生成配合物 。它抑制从 克氏锥虫中提纯的 NADH 富马酸还原酶 。它是 O -酰基硫代异羟酸盐的前体 。它与金属连接形成具有生物活性的复合物 。
应用
2-巯基吡啶 N -氧化物被用于研究巯基吡啶- N -氧化物杀菌剂的光降解机理 。它被用于哺乳动物细胞内锌离子的比率荧光成像 。
O-酰基硫代异羟化物的前体。与金属连接形成具有生物活性的复合物。
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Matias Butler et al.
Journal of mass spectrometry : JMS, 52(11), 728-738 (2017-07-26)
2-Mercaptopyridine N-oxide (pyrithione, PTOH) along with several transition metal ions forms coordination compounds displaying notable biological activities. Gas-phase complexes formed between pyrithione and manganese (II), cobalt (II), nickel (II), copper (II), and zinc (II) were investigated by infusion in the
Christopher J Chang et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(5), 1129-1134 (2004-01-22)
Zinc is an essential metal ion for human growth and development, the disruption of cellular Zn(2+) homeostasis being implicated in several major disorders including Alzheimer's disease, diabetes, and cancer. The molecular mechanisms of Zn(2+) physiology and pathology are insufficiently understood
Photodegradation of mercaptopyridine-N-oxide biocides.
R A Neihof et al.
Archives of environmental contamination and toxicology, 8(3), 355-368 (1979-01-01)
J F Turrens et al.
FEMS microbiology letters, 175(2), 217-221 (1999-07-01)
The enzyme NADH-fumarate reductase is not found in mammalian cells but it is present in several parasitic protozoa including Trypanosoma cruzi, the parasite that causes Chagas' disease. This study shows that the drug 2-mercaptopyridine-N-oxide (MPNO) inhibits NADH-fumarate reductase purified from
Vesna Lavtizar et al.
Ecotoxicology and environmental safety, 147, 132-138 (2017-08-26)
Copper pyrithione (CuPT) is a biocide, used worldwide to prevent biofouling on submerged surfaces. In aquatic environments it rapidly degrades, however, one of the degradation products (HPT) is known to react with cupric ion back to its parent compound. Not
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