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Merck
CN

184837

Sigma-Aldrich

)-2-氨基-3-甲基-1-丁醇

97%

别名:

DL-缬氨醇

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About This Item

线性分子式:
(CH3)2CHCH(NH2)CH2OH
CAS号:
分子量:
103.16
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

检测方案

97%

形式

liquid

折射率

n20/D 1.4543 (lit.)

bp

75-77 °C/8 mmHg (lit.)

密度

0.936 g/mL at 25 °C (lit.)

SMILES字符串

CC(C)C(N)CO

InChI

1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3

InChI key

NWYYWIJOWOLJNR-UHFFFAOYSA-N

应用

2-氨基-3-甲基-1-丁醇被用于合成1-烯丙基-2-吡咯烷酮。 它也被用作手性亲核试剂,用于合成贝娜诺霉素-普纳米星类抗生素。在合成包含两个手性亚基的冠醚时,它被用作同手性客体化合物

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

194.0 °F

闪点(°C)

90 °C

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Andrei V Malkov et al.
Chemical communications (Cambridge, England), (15)(15), 1948-1949 (2003-08-23)
New N,P-ligands 4-6, derived from valinol and prolinol, respectively, have been developed for the asymmetric, copper(I)-catalysed conjugate addition of diethylzinc to unsaturated ketones; the tertiary amide group has been shown to effectively relay the chiral information from the ligand backbone
Preparation of homochiral phenolic crown ethers containing para-substituted phenol moiety and chiral subunits derived from (S)-1-phenylethane-1, 2-diol: their chiral recognition behaviour in complexation with neutral amines.
Naemura K, et al.
Tetrahedron Asymmetry, 8(6), 873-882 (1997)
Vincenzo Giulio Albano et al.
The Journal of organic chemistry, 73(21), 8376-8381 (2008-10-02)
1-Allyl-2-pyrroleimines obtained from (S)-valinol and (S)-phenylglycinol underwent highly diastereoselective addition of allylmagnesium chloride, used in excess amounts, to give the corresponding secondary amines with concomitant allyl to (Z)-1-propenyl isomerization of the 1-pyrrole substituent. Transformation of the 2-amino alcohol moiety to
Kun Huang et al.
The Journal of organic chemistry, 73(11), 4017-4026 (2008-05-02)
An asymmetric synthesis for the preparation of nonracemic amines bearing heterocyclic and heteroaromatic rings is described. A variety of important enantiopure thionyl and arylalkyl primary amines were afforded by the borane-mediated enantioselective reduction of O-benzyl ketoximes using 10% of catalyst
E Spitzer et al.
Biochemistry international, 14(4), 581-588 (1987-04-01)
A procedure for purification of plasma membranes from bovine mammary gland has been developed. The binding capacity of EGF to the plasma membranes from mammary tissue of pregnant cows was equal to 335 fmol per mg of protein thus being

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