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Merck
CN

184462

Sigma-Aldrich

氯甲酸丁酯

98%

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线性分子式:
ClCOOCH2CH2CH2CH3
CAS号:
分子量:
136.58
Beilstein:
605635
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

2.42 psi ( 20 °C)

质量水平

检测方案

98%

形式

liquid

折射率

n20/D 1.412 (lit.)

bp

142 °C (lit.)

密度

1.074 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CCCCOC(Cl)=O

InChI

1S/C5H9ClO2/c1-2-3-4-8-5(6)7/h2-4H2,1H3

InChI key

NRDQFWXVTPZZAZ-UHFFFAOYSA-N

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应用

  • Butyl chloroformate was used in the synthesis of dextran alkyl carbonates.
  • It was also used in the synthesis of S-tert-alkyl-N,N-alkoxycarbonylmethyl-dithiocarbamate, radical polymerization with reversible addition-fragmentation chain transfer agent.
  • It was used as derivatization reagent in determination of linsidomine in plasma using high-performance liquid chromatographic separation with tandem mass spectrometric detection.

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Inhalation - Flam. Liq. 3 - Skin Corr. 1B

WGK

WGK 1

闪点(°F)

100.4 °F

闪点(°C)

38 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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F C Sutherland et al.
Journal of pharmaceutical and biomedical analysis, 22(3), 461-467 (2000-04-15)
A sensitive method for the determination of linsidomine in plasma was developed, using high-performance liquid chromatographic (HPLC) separation with tandem mass spectrometric detection. Linsidomine was derivatised with propyl chloroformate and extracted with tert-butyl methyl ether/1,2-dichloroethane (55:45, v/v), back-extracted into HCl
Multiblock copolymer synthesis via controlled radical polymerization in aqueous dispersions. Part 1: Synthesis of S-tert-alkyl-N,N-alkoxycarbonylmethyl-dithiocarbamate.
Bussels R and Koning CE.
Tetrahedron, 61(5), 1167-1174 (2005)
Andrea Y Garzón-Serrano et al.
Journal of forensic sciences, 65(4), 1085-1093 (2020-03-17)
Ammonium nitrate fuel oil is an explosive mixture found in most antipersonnel landmines (APL) buried throughout the Colombian territory. During more than 50 years of internal conflict, the Colombian government has found that trained dogs are the most effective method to
Tomáš Hložek et al.
Journal of analytical toxicology, 40(9), 749-753 (2016-09-04)
A simple, sensitive and robust method for simultaneous determination of antiepileptic drugs (gabapentin, pregabalin and vigabatrin) in human serum using GC-MS was developed and validated for clinical toxicology purposes. This method employs an emerging class of derivatization agents - alkyl
Thomas Elschner et al.
Carbohydrate polymers, 93(1), 216-223 (2013-03-08)
Dextran alkyl carbonates were synthesized applying ethyl chloroformate, butyl chloroformate, butyl fluoroformate and 1H-imidazole-1-carboxylates. The influence of the reaction conditions on the reaction efficiency and the substitution pattern was studied in detail. The structure of the products obtained was clearly

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