质量水平
检测方案
98%
杂质
<2% diphenyl selenide
mp
59-61 °C (lit.)
SMILES字符串
[Se]([Se]c1ccccc1)c2ccccc2
InChI
1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H
InChI key
YWWZCHLUQSHMCL-UHFFFAOYSA-N
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一般描述
二苯二硒化物是一种有机硒化合物，是苯硒醇的氧化衍生物。它是苯基硒自由基的来源。它能与多种有机亲核试剂、亲电试剂和自由基反应。
应用
二苯二硒化物的用途：在铜铁氧体纳米颗粒催化剂的存在下，通过芳基卤化物与二苯二砷化物的交叉偶联合成硒化二芳基物。
生化/生理作用
二苯基二硒化物在体内抑制脑、肝和肾脏中的δ-氨基乙酰丙酸脱水酶（δ-ALA-D）。
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
危险化学品
Juliana Trevisan da Rocha et al.
Neurobiology of learning and memory, 99, 17-24 (2012-10-23)
This study investigated the effects of co-administration of diphenyl diselenide [(PhSe)(2)] and 17β-estradiol (E(2)) on spatial reference, recognition, and working memories in ovariectomized (OVX) female mice. Sixty-day-old female adult Swiss mice were submitted to ovariectomy. From the 30th until 32nd
Viviane Glaser et al.
Chemico-biological interactions, 206(1), 18-26 (2013-08-21)
Interest in organoselenide chemistry and biochemistry has increased in the past three decades, mainly due to their chemical and biological activities. Here, we investigated the protective effect of the organic selenium compound diphenyl diselenide (PhSe)2 (5 μmol/kg), in a mouse
Michele Hinerasky da Silva et al.
Neurotoxicity research, 21(3), 334-344 (2011-11-15)
Organoselenium compounds exhibit antioxidant activity, as well as a variety of biological activities, with potential pharmacological and therapeutic applications. The aim of this study was to investigate the effect of diphenyl diselenide (PhSe)(2) in reversing oxidative brain damage and mitochondrial
Glaecir Roseni Mundstock Dias et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 30(2), 83-89 (2012-01-17)
Cognitive deficits have been observed in different animal models of adult-onset hypothyroidism. Thus, this study was delineated to evaluate whether diphenyl diselenide, an organoselenium compound with neuroprotective and antioxidant properties, could afford protection against the detrimental effects of hypothyroidism on
César Augusto Brüning et al.
Progress in neuro-psychopharmacology & biological psychiatry, 38(2), 168-174 (2012-03-31)
Bipolar disorder (BD) is a common and severe mood disorder associated with higher rates of suicide and disability. Ouabain, a Na(+)/K(+)-ATPase inhibitor, induces behavioral changes in rats and has been used as a model of mania. The aim of this
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