质量水平
检测方案
98%
形式
liquid
折射率
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
密度
0.85 g/mL at 25 °C (lit.)
SMILES字符串
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
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一般描述
IPM是一种脂肪酸酯，可由异丙基醇和肉豆蔻酸的酯化产生。
应用
处方制备中使用肉豆蔻酸异丙酯作为油相 。也用作油/水型他克莫司 (FK506) 溶剂 。
储存分类代码
10 - Combustible liquids
WGK
awg
闪点(°F)
>302.0 °F
闪点(°C)
> 150 °C
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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We developed an oil/water-type tacrolimus (FK506) cream formulation as an alternative to Protopic ointment for atopic dermatitis treatment. We determined the effects of solvents used in topical preparations on FK506 solubility and stability, and evaluated FK506 transdermal absorption into rat
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