质量水平
检测方案
97%
形式
solid
mp
226-230 °C (lit.)
SMILES字符串
Nc1nc2ccccc2[nH]1
InChI
1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)
InChI key
JWYUFVNJZUSCSM-UHFFFAOYSA-N
基因信息
human ... PLAU(5328)
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应用
2-氨基苯并咪唑用于碳酸胆碱的水解 。它还用于咪唑并 [1,2-a] 苯并咪唑的合成 。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Ya-Shan Hsiao et al.
ACS combinatorial science, 15(10), 551-555 (2013-09-11)
A one-pot, two-step synthesis of imidazo[1,2-a]benzimidazoles has been achieved by a three-component reaction of 2-aminobenzimidazoles with an aromatic aldehyde and an isocyanide. The reaction involving condensation of 2-aminobenzimidazole with an aldehyde is run under microwave activation to generate an imine
Bartolomé Soberats et al.
Organic letters, 16(3), 840-843 (2014-01-15)
The hydrolysis of a choline carbonate through a metal-free, enzyme-like mechanism has been achieved using a 2-aminobenzimidazole-based deep cavitand as catalyst. The supramolecular catalysis involves three steps: host-guest binding, carbamoylation and enzyme-like hydrolysis. Interestingly the rate-determining step proceeds through a
Timothy Coon et al.
Bioorganic & medicinal chemistry letters, 19(15), 4380-4384 (2009-06-26)
The benzimidazole core of the selective non-brain-penetrating H(1)-antihistamine mizolastine was used to identify a series of brain-penetrating H(1)-antihistamines for the potential treatment of insomnia. Using cassette PK studies, brain-penetrating H(1)-antihistamines were identified and in vivo efficacy was demonstrated in a
Kazuya Kikuchi et al.
Bioorganic & medicinal chemistry, 14(18), 6189-6196 (2006-06-20)
Antibodies that catalyze the deprotonation of unactivated benzisoxazoles to give the corresponding salicylonitriles were prepared using as antigen a 2-aminobenzimidazolium derivative coupled to a carrier protein via its benzene ring. The hapten was designed to induce an antibody binding site
2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms.
Reto Frei et al.
Angewandte Chemie (International ed. in English), 51(21), 5226-5229 (2012-04-11)
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