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Merck
CN

165956

Sigma-Aldrich

苯磺酸甲酯

98%

别名:

Benzenesulfonic acid methyl ester, Benzenesulfonic acid, methyl ester, Methyl benzenesulphonate, Methyl besylate, methyl ester of benzenesulphonic acid

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About This Item

经验公式(希尔记法):
C7H8O3S
CAS号:
分子量:
172.20
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

形式

liquid

储存温度

2-8°C

SMILES字符串

COS(=O)(=O)c1ccccc1

InChI

1S/C7H8O3S/c1-10-11(8,9)7-5-3-2-4-6-7/h2-6H,1H3

InChI key

CZXGXYBOQYQXQD-UHFFFAOYSA-N

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应用

苯磺酸甲酯可作为甲基化试剂:
  • 用于四溴噻吩的C-甲基化反应在丁基锂的存在下合成三溴-甲基噻吩。
  • 用于镍催化下惰性卤代烃和酰氯经甲基化反应制备甲基化烷烃和酮。
还可作为反应剂,用于sophoridinol(槐定醇)衍生物醚化生成sophoridinol的N-取代甲基醚衍生物。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Julian L Goggi et al.
Molecular imaging and biology, 22(4), 993-1002 (2020-02-02)
Cancer immunotherapy has shown huge potential in the fight against cancer, but only a small proportion of patients respond successfully to treatment. Non-invasive methods to stratify responders from non-responders are critically important as immune therapies are often associated with immune-related
Zhen Liu et al.
Journal of pharmaceutical and biomedical analysis, 168, 23-29 (2019-02-21)
Alkyl sulfonate esters have been widely concerned as genotoxic impurities (GTIs). A gas chromatography triple-quadrupole mass spectrometry (GC-MS/MS) method has been developed for trace determination of 9 commonly encountered sulfonate esters in drug substances. Three different solvents of acetonitrile (ACN)

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