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162906

Sigma-Aldrich

2-羟基-5-硝基苄溴

90%

别名:

α-溴-4-硝基邻甲酚, 2-溴甲基-4-硝基苯酚, Koshland I, Koshland 试剂 I

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5 MG
¥1,051.72
25 MG
¥2,828.99
100 MG
¥9,319.60

¥1,051.72

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5 MG
¥1,051.72
25 MG
¥2,828.99
100 MG
¥9,319.60

About This Item

线性分子式:
HOC6H3(NO2)CH2Br
CAS号:
772-33-8
分子量:
232.03
Beilstein:
1868798
EC 号:
212-248-9
MDL编号:
MFCD00007340
UNSPSC代码:
12352100
PubChem化学物质编号:
24850013
NACRES:
NA.22

¥1,051.72

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方案

90%

表单

solid

mp

144-149 °C (lit.)

溶解性

chloroform: soluble 25 mg/mL, clear, yellow

官能团

bromo
nitro

储存温度

2-8°C

SMILES字符串

Oc1ccc(cc1CBr)[N+]([O-])=O

InChI

1S/C7H6BrNO3/c8-4-5-3-6(9(11)12)1-2-7(5)10/h1-3,10H,4H2

InChI key

KFDPCYZHENQOBV-UHFFFAOYSA-N

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Copper - O.F.H.C. foil, 10m coil, thickness 0.010mm, coil width 25mm, hard, 99.95+%

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Copper - O.F.H.C. foil, 5m coil, thickness 0.010mm, coil width 25mm, hard, 99.95+%

GF60882183

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manufacturer/tradename

Goodfellow 104-251-69

manufacturer/tradename

Goodfellow 917-764-59

manufacturer/tradename

Goodfellow 496-482-36

manufacturer/tradename

Goodfellow 608-821-83

assay

99.95%

assay

≥99.95%

assay

99.95%

assay

99.95%

resistivity

1.673 μΩ-cm, 20°C

resistivity

1.673 μΩ-cm, 20°C

resistivity

1.673 μΩ-cm, 20°C

resistivity

1.673 μΩ-cm, 20°C

density

8.94 g/mL at 25 °C (lit.)

density

8.94 g/mL at 25 °C (lit.)

density

8.94 g/mL at 25 °C (lit.)

density

8.94 g/mL at 25 °C (lit.)

mp

1083.4 °C (lit.)

mp

1083.4 °C (lit.)

mp

1083.4 °C (lit.)

mp

1083.4 °C (lit.)

一般描述

2-Hydroxy-5-nitrobenzyl bromide is a protein modifying reagent[1].

应用

2-Hydroxy-5-nitrobenzyl bromide was used in covalent modification of tryptophan[2] and tryptophan residues in monoclonal immunoglobulin[3]. It was also used as reagent for sulfhydryl modification[4]

其他说明

含有 2-羟基-5-硝基苯甲醇

象形图

Corrosion
GHS05

警示用语：

Danger

危险声明

H314

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000140474
    0000140474
    MKBG5488V
    09508DD
    16426CR

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    Hee Seung Kim et al.
    Electrophoresis, 23(6), 956-963 (2002-03-29)
    A technique based on affinity capillary electrophoresis (ACE) and chemically modified proteins was used to screen the binding sites of various drugs on human serum albumin (HSA). This involved using HSA as a buffer additive, following the site-selective modification of
    Arunas Silanskas et al.
    Biochemistry, 50(14), 2800-2807 (2011-03-18)
    Regulation of proteins by light is a new and promising strategy for the external control of biological processes. In this study, we demonstrate the ability to regulate the catalytic activity of the MunI and PvuII restriction endonucleases with light. We
    M Sabés et al.
    Journal of biochemical and biophysical methods, 17(1), 17-24 (1988-09-01)
    The use of 2-hydroxy-5-nitrobenzyl bromide for the modification of tryptophan residues in integral membrane proteins is exemplified by its application to bacteriorhodopsin from Halobacterium halobium. Complete elimination of the unreacted reagent requires delipidation of the sample with detergents and posterior
    C Locht et al.
    Proceedings of the National Academy of Sciences of the United States of America, 86(9), 3075-3079 (1989-05-01)
    The enzymatic ADP-ribosyltransferase activity associated with the S1 subunit of pertussis toxin is considered to be responsible for its biological effects. Although pertussis toxin has no significant homology to other ADP-ribosylating toxins such as diphtheria toxin and Pseudomonas aeruginosa exotoxin
    C Nishimura et al.
    European journal of biochemistry, 196(2), 377-384 (1991-03-14)
    Oxidation of the Met residues of human interleukin 6 (IL-6) molecule has been performed. Reactivity of Met for the oxidation reaction was found to decrease in the order of Met50, Met118, Met185, Met162, and Met68. Chemical modifications involving oxidation and
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