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About This Item
经验公式（希尔记法）:
C16H14N2O2
CAS号:
分子量:
266.29
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
质量水平
检测方案
≥99%
形式
powder
mp
225-226 °C (lit.)
溶解性
soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow (DMF:HCl(2:1))
SMILES字符串
Cc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
InChI
1S/C16H14N2O2/c1-11-7-9-13(10-8-11)16(12-5-3-2-4-6-12)14(19)17-15(20)18-16/h2-10H,1H3,(H2,17,18,19,20)
InChI key
WPAPSGQWYNPWCZ-UHFFFAOYSA-N
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应用
5-(p-Methylphenyl)-5-phenylhydantoin was used as internal standard in quantitative determination of phenytoin in brain microdialysate, saliva and blood from human samples by GC-MS method . It was used in DMD-test to determine chromatographic properties of C8- or C18-bonded phases for clinical and forensic toxicological screening.
Reactant for synthesis of N-chlorohydantoins
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2 - Repr. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
A simple test to characterise C8/C18-bonded phases, particularly for toxicological screening.
Daldrup T and Kardel B.
Chromatographia, 18(2), 81-83 (1984)
T M Hassell et al.
Epilepsia, 25(5), 556-563 (1984-10-01)
The metabolism of sodium phenytoin (PHT) in the cat was studied by gas-liquid chromatographic analyses of the drug and its metabolites extracted from plasma, urine, and feces during a 5-month course of daily oral administration. Plasma PHT levels of 15-18
Jean-Baptiste Rivière et al.
Nature genetics, 44(8), 934-940 (2012-06-26)
Megalencephaly-capillary malformation (MCAP) and megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndromes are sporadic overgrowth disorders associated with markedly enlarged brain size and other recognizable features. We performed exome sequencing in 3 families with MCAP or MPPH, and our initial observations were confirmed in exomes
Helena Fels et al.
Forensic science international, 277, e30-e35 (2017-05-17)
In this study, two fatalities associated with the synthetic opioids AH-7921 and MT-45 are reported. Within the last few years, both compounds have emerged on the recreational drug market and are sold as "research chemicals" on the internet. In the
M Riedmann et al.
Therapeutic drug monitoring, 3(4), 397-413 (1981-01-01)
Specific antiepileptic drug (AED) concentrations in serum are believed to cause therapeutic effects in individual patients. Communication between the clinician and the laboratory performing the drug level determinations is therefore essential for safe and effective medication. The now common practice
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