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Merck
CN

160660

喹哪啶酸

98%

别名:

2-喹啉羧酸

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关于此项目

经验公式(希尔记法):
C10H7NO2
化学文摘社编号:
分子量:
173.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-218-3
Beilstein/REAXYS Number:
126322
MDL number:
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产品名称

喹哪啶酸, 98%

InChI key

LOAUVZALPPNFOQ-UHFFFAOYSA-N

InChI

1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13)

SMILES string

OC(=O)c1ccc2ccccc2n1

assay

98%

form

solid

mp

156-158 °C (lit.)

functional group

carboxylic acid

Quality Level

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General description

喹啉酸也称为喹啉-2-羧酸。已报告微波辅助合成喹啉酸取代苯胺的方法。抑制丙酮酸盐的氧化,α-大鼠肝线粒体中的酮戊二酸、谷氨酸和柠檬酸。喹啉酸是色氨酸降解的代谢产物,抑制灌注肝脏中的糖异生。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Total synthesis of thiostrepton, part 2: construction of the quinaldic acid macrocycle and final stages of the synthesis.
K C Nicolaou et al.
Angewandte Chemie (International ed. in English), 43(38), 5092-5097 (2004-09-17)
R M Epand
Medical hypotheses, 9(2), 207-213 (1982-08-01)
Ergothioneine is believed not to be synthesized by man but it accumulates to high concentrations in some mammalian cells as a result of dietary intake. Ergothioneine is known to chelate divalent metal ions with high affinity. Other substances which are
Mode of action of hypoglycemic agents. 3. Studies on 5-methoxy indole-2-carboxylic acid and quinaldic acid.
J Reed et al.
The Journal of biological chemistry, 245(20), 5297-5303 (1970-10-25)
S Fetzner et al.
Biological chemistry Hoppe-Seyler, 374(6), 363-376 (1993-06-01)
Serratia marcecens 2CC-1 utilizes quinaldic acid (quinoline 2-carboxylic acid) as sole source of carbon, nitrogen and energy. Growth of strain 2CC-1 on quinaldic acid as well as on nicotinic acid and hypoxanthine was inhibited completely by the molybdate antagonist tungstate
Zhao-Qing Du et al.
Journal of Cancer, 11(15), 4614-4624 (2020-06-04)
Platelet-derived growth receptor α (PDGFRα) is a key factor in many pathophysiological processes. The expression level of PDGFRα is significantly elevated in the early stage of liver development and maintained at a lower level in adult normal livers. In this

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