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Merck
CN

158992

Sigma-Aldrich

对甲苯磺酸甲酯

98%

别名:

Methyl p-methylbenzenesulfonate, Methyl toluene-4-sulfonate, Methyl tosylate, Methylp-tosylate

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About This Item

线性分子式:
CH3C6H4SO3CH3
CAS号:
分子量:
186.23
Beilstein:
609209
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

6.45 (vs air)

质量水平

蒸汽压

1 mmHg ( 20 °C)

方案

98%

表单

solid

自燃温度

896 °F

折射率

n20/D 1.5172 (lit.)

沸点

144-145 °C/5 mmHg (lit.)

mp

25-28 °C (lit.)

密度

1.234 g/mL at 25 °C (lit.)

官能团

tosylate

储存温度

2-8°C

SMILES字符串

COS(=O)(=O)c1ccc(C)cc1

InChI

1S/C8H10O3S/c1-7-3-5-8(6-4-7)12(9,10)11-2/h3-6H,1-2H3

InChI key

VUQUOGPMUUJORT-UHFFFAOYSA-N

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一般描述

甲苯磺酸甲酯是一种磺酸酯类,作为一种潜在遗传毒性杂质存在于药物中。目前甲苯磺酸甲酯与N、N-二甲基苯胺的反应动力学已经过研究。其参与了四唑的选择性1取代反应。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 2

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Secondary deuterium isotope effects.. beta.-Kinetic effects in Sn2 reactions of N, N-dimethylaniline and dimethylphenylphosphine with methyl p-toluenesulfonate, and comparison with observed and calculated vibrational frequencies.
Kaplan ED and Thornton ER.
Journal of the American Chemical Society, 89(25), 6644-6651 (1967)
The formation of tin-nitrogen bonds. V. The selective 1-substitution reaction of tetrazoles by the reaction of 5-substituted 2-(tri-n-butylstannyl) tetrazoles with methyl iodide, methyl p-toluenesulfonate, dimethyl sulfate, and ethyl bromoacetate.
Isida T, et al.
Bulletin of the Chemical Society of Japan, 46, 2176-2180 (1973)
Bryn D Monnery et al.
International journal of pharmaceutics, 521(1-2), 249-258 (2017-02-25)
The mechanism of polycation cytotoxicity and the relationship to polymer molecular weight is poorly understood. To gain an insight into this important phenomenon a range of newly synthesised uniform (near monodisperse) linear polyethylenimines, commercially available poly(l-lysine)s and two commonly used
Joachim F R Van Guyse et al.
Polymers, 13(3) (2021-02-04)
Smart or adaptive materials often utilize stimuli-responsive polymers, which undergo a phase transition in response to a given stimulus. So far, various stimuli have been used to enable the modulation of drug release profiles, cell-interactive behavior, and optical and mechanical
Polen Kocak et al.
Macromolecular bioscience, 21(2), e2000287-e2000287 (2020-11-17)
Prostate cancer is the most common cancer, which is about 15-20% among male cancers worldwide. As most common strategies such as radiotherapy, chemotherapy, or surgery alone can be unsuccessful in the treatment of prostate cancer, this study aims to develop

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