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Merck
CN

158186

Sigma-Aldrich

乙二胺-N,N′-二乙酸

≥98%

别名:

EDDA, N,N′-乙烯二甘氨酸

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About This Item

线性分子式:
HOOCCH2NHCH2CH2NHCH2COOH
CAS号:
分子量:
176.17
Beilstein:
1778355
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥98%

mp

224 °C (dec.) (lit.)

SMILES字符串

OC(=O)CNCCNCC(O)=O

InChI

1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)

InChI key

IFQUWYZCAGRUJN-UHFFFAOYSA-N

应用

乙二胺-N,N′-二乙酸(EDDA)是一种螯合剂,可用于合成:
  • 具有高蛋白酶体抑制性能的二元和三元铜(II)配合物。
  • 可以与氨基酸、肽或DNA单元络合的Pd(EDDA)配合物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Hoi-Ling Seng et al.
Journal of inorganic biochemistry, 102(11), 1997-2011 (2008-09-10)
The binding selectivity of the M(phen)(edda) (M=Cu, Co, Ni, Zn; phen=1,10-phenanthroline, edda=ethylenediaminediacetic acid) complexes towards ds(CG)(6), ds(AT)(6) and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is intercalation and there is selectivity towards
Karla Mettrick et al.
Antibiotics (Basel, Switzerland), 9(4) (2020-04-02)
Targeting the iron requirement of Pseudomonas aeruginosa may be an effective adjunctive for conventional antibiotic treatment against biofilm-dwelling P. aeruginosa. We, therefore, assessed the anti-biofilm activity of N,N'-bis (2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid (HBED), which is a synthetic hexadentate iron chelator. The
Olivier Dalmas et al.
Structure (London, England : 1993), 18(7), 868-878 (2010-07-20)
The transmembrane conformation of Thermotoga maritima CorA, a magnesium transport system, has been studied in its Mg(2+)-bound form by site-directed spin labeling and electron paramagnetic resonance spectroscopy. Probe mobility together with accessibility data were used to evaluate the overall dynamics
Giuseppe Palladino et al.
Dalton transactions (Cambridge, England : 2003), (43)(43), 5176-5183 (2006-11-02)
The structure, thermodynamics and kinetics of the binary and ternary uranium(VI)-ethylenediamine-N,N'-diacetate (in the following denoted EDDA) fluoride systems have been studied using potentiometry, 1H, 19F NMR spectroscopy and X-ray diffraction. The UO2(2+)-EDDA system could be studied up to -log[H3O+] =
Structural characterization, ROS-inductive and proteasome inhibitory properties of ternary and binary copper (II) complexes of N2- and N2O2-ligands.
Chan CW, et al.
Inorgorganica Chimica Acta, 450, 202-210 (2016)

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