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质量水平
方案
≥98%
mp
224 °C (dec.) (lit.)
官能团
amine
carboxylic acid
SMILES字符串
OC(=O)CNCCNCC(O)=O
InChI
1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)
InChI key
IFQUWYZCAGRUJN-UHFFFAOYSA-N
应用
乙二胺-N，N′-二乙酸（EDDA）是一种螯合剂，可用于合成：
- 具有高蛋白酶体抑制性能的二元和三元铜（II）配合物。
- 可以与氨基酸、肽或DNA单元络合的Pd（EDDA）配合物。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Alma D Miranda-Olvera et al.
Bioconjugate chemistry, 18(5), 1560-1567 (2007-08-02)
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position
Hyun-Shik Chang et al.
Environmental science & technology, 40(16), 5089-5094 (2006-09-08)
Permanganate has been used for oxidation of nuclear wastes containing chelating agents such as ethylenediaminetetraacetic and nitrilotriacetic acids (EDTA and NTA) to improve separation of radionuclides and heavy metals from the wastes, butthe mechanisms of degradation of these and related
Clara L Santos-Cuevas et al.
Nuclear medicine communications, 29(8), 741-747 (2008-08-30)
The gastrin-releasing peptide receptor (GRP-R) is expressed in several normal human tissues and is overexpressed in various human tumors including breast, prostate, small-cell lung cancer and pancreatic cancer. Recently, 99mTc-EDDA/HYNIC-[Lys]-bombesin (99mTc-HYNIC-BN) was reported as a radiopharmaceutical with high stability in
Jelena M Vujić et al.
European journal of medicinal chemistry, 45(9), 3601-3606 (2010-06-24)
Four novel bidentate N,N'-ligand precursors, including O,O'-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), L1 x 2 HCl-L4 x 2 HCl, of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid dihydrochloride [(S,S)-H(4)eddl]Cl(2) and the corresponding palladium(II) complexes 1-4, were prepared and characterized by IR, (1)H
Levente K Meszaros et al.
Dalton transactions (Cambridge, England : 2003), 40(23), 6260-6267 (2011-02-26)
6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous
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