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质量水平
方案
98%
表单
solid
mp
99-105 °C (lit.)
溶解性
water: soluble 50 mg/mL, clear, colorless
储存温度
2-8°C
SMILES字符串
CC(=O)n1ccnc1
InChI
1S/C5H6N2O/c1-5(8)7-3-2-6-4-7/h2-4H,1H3
InChI key
VIHYIVKEECZGOU-UHFFFAOYSA-N
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一般描述
酸溶液中1-乙酰基咪唑的溶剂分解速率被得以评估。1-乙酰基咪唑与正磷酸盐和腺苷-5′-磷酸盐的反应已被报道。
应用
1-乙酰基咪唑被用作氨基的乙酰化试剂。它还可用于组蛋白的乙酰化。
酪氨酰残基乙酰化的相对特异性试剂。该试剂用于合成环状咪唑衍生物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
The Solvolysis of 1-Acetylimidazole in Concentrated Acid and Salt Solutions.
Marburg S and Jencks WP.
Journal of the American Chemical Society, 84(2), 232-239 (1962)
Variation of the nuclear, subnuclear and chromosomal flavanol deposition in hemlock and rye.
Feucht W, et al.
International Journal of Molecular Sciences, 8(7), 635-650 (2007)
Chemische Berichte, 125, 1939-1939 (1992)
I Wells et al.
Biochemistry, 31(40), 9520-9525 (1992-10-13)
Treatment of prostaglandin endoperoxide (PGH) synthase apoprotein with a 100- or 1000-fold excess of N-acetylimidazole (NAI) led to time-dependent inactivation of both cyclooxygenase and peroxide activities. Reconstitution of apoprotein with heme prior to incubation with NAI substantially protected the enzyme
The Reaction of 1-Acetylimidazole with Orthophosphate*.
Brinigar WS and Knaff DB.
Biochemistry, 4(3), 406-409 (1965)
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