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Merck
CN

156035

Sigma-Aldrich

3-(三氟甲基)苯酚

99%

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别名:
α,α,α-三氟间甲酚, 间三氟甲基苯酚
线性分子式:
CF3C6H4OH
CAS号:
分子量:
162.11
Beilstein:
2045663
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

0.56 mmHg ( 40 °C)

质量水平

检测方案

99%

形式

liquid

折射率

n20/D 1.458 (lit.)

bp

178-179 °C (lit.)

mp

−2-−1.8 °C (lit.)

密度

1.333 g/mL at 25 °C (lit.)

SMILES字符串

Oc1cccc(c1)C(F)(F)F

InChI

1S/C7H5F3O/c8-7(9,10)5-2-1-3-6(11)4-5/h1-4,11H

InChI key

UGEJOEBBMPOJMT-UHFFFAOYSA-N

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应用

3-(Trifluoromethyl)phenol (3-Hydroxybenzotrifluoride) was used in the preparation of travoprost (antiglaucoma agent).

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Boulton LT, et al.
Organic Process Research & Development, 6(2), 138-145 (2002)
Akira Ohashi et al.
Talanta, 146, 789-794 (2015-12-24)
The solubilities of several cobalt(III) chelates (CoL3) with in supercritical carbon dioxide (SC-CO2) were investigated in the presence of fluorine- and trifluoromethyl-substituted phenols (PhOH) using UV-vis spectrophotometry. Solubility enhancement of CoL3 complexes in SC-CO2 was accomplished by adding PhOH. The
The many roles for fluorine in medicinal chemistry.
William K Hagmann
Journal of medicinal chemistry, 51(15), 4359-4369 (2008-06-24)

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