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Merck
CN

15500

Sigma-Aldrich

N-(叔丁氧羰基)-L-丝氨酸

≥99.0% (T), for peptide synthesis

别名:

N-(叔丁氧羰基)-L-丝氨酸, Boc-L-丝氨酸

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About This Item

线性分子式:
HOCH2CH(COOH)NHCOOC(CH3)3
CAS号:
分子量:
205.21
Beilstein:
2212252
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22

产品名称

N-(叔丁氧羰基)-L-丝氨酸, ≥99.0% (T)

质量水平

方案

≥99.0% (T)

旋光性

[α]20/D −3.5±0.5°, c = 2% in acetic acid

反应适用性

reaction type: Boc solid-phase peptide synthesis

mp

91 °C (dec.) (lit.)

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O

InChI

1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1

InChI key

FHOAKXBXYSJBGX-YFKPBYRVSA-N

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一般描述

Boc-Ser-OH是一种氨基酸衍生物。

应用

Boc-Ser-OH可用于以下合成:
  • 2-(N-Fmoc)-3-(N-BOC-N-甲氧基)-二氨基丙酸(Fmoc:9-芴基甲氧基羰基;Boc:叔丁氧基羰基)
  • Boc-Ser-Leu-OMe
  • 环肽合成
  • 苄基磺酰基-D-Ser-Ser-4-氨基苄酰胺
肽合成中的结构单元。用于通过 β-内酯合成各种 α-氨基酸的原料。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis of cyclic peptides via O-N-acyl migration.
Lecaillon J, et al.
Tetrahedron Letters, 49(31), 4674-4676 (2008)
M Komai-Koma et al.
Immunology, 91(4), 579-585 (1997-08-01)
The chemoattractant effect of soluble protein antigens for B cells from immunized mice was examined. Mice were immunized either via the footpad with ovalbumin (OVA) in complete Freund's adjuvant (CFA) or with CFA alone; or intraperitoneally with OVA incorporated in
The relationship between taste and primary structure of ?delicious peptide?(Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) from beef soup.
Tamura M, et al.
Agricultural and Biological Chemistry, 53(2), 319-325 (1989)
Michael R Carrasco et al.
Biopolymers, 84(4), 414-420 (2006-03-02)
Amino acids with N-alkylaminooxy side chains have proven effective for the rapid synthesis of neoglycopeptides. Chemoselective reaction of reducing sugars with peptides containing these amino acids provides glycoconjugates that are structurally similar to their natural counterparts. 2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl;
O García-Suárez et al.
Immunology, 94(2), 235-241 (1998-09-19)
Increasing evidence suggests that some members of the neurotrophic factor family of neurotrophins could be implicated in the regulation of immune responses. Neurotrophins, as well as their tyrosine kinase signal-transducing receptors (the so-called Trk neurotrophin receptors), have been detected in

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