15500
N-(叔丁氧羰基)-L-丝氨酸
≥99.0% (T), for peptide synthesis
别名:
N-(叔丁氧羰基)-L-丝氨酸, Boc-L-丝氨酸
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关于此项目
线性分子式:
HOCH2CH(COOH)NHCOOC(CH3)3
化学文摘社编号:
分子量:
205.21
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
221-867-3
MDL number:
Beilstein/REAXYS Number:
2212252
产品名称
N-(叔丁氧羰基)-L-丝氨酸, ≥99.0% (T)
InChI key
FHOAKXBXYSJBGX-YFKPBYRVSA-N
InChI
1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1
SMILES string
CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O
assay
≥99.0% (T)
optical activity
[α]20/D −3.5±0.5°, c = 2% in acetic acid
reaction suitability
reaction type: Boc solid-phase peptide synthesis
mp
91 °C (dec.) (lit.)
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
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General description
Boc-Ser-OH是一种氨基酸衍生物。
Application
Boc-Ser-OH可用于以下合成：
- 2-（N-Fmoc）-3-（N-BOC-N-甲氧基）-二氨基丙酸（Fmoc：9-芴基甲氧基羰基；Boc：叔丁氧基羰基）
- Boc-Ser-Leu-OMe
- 环肽合成
- 苄基磺酰基-D-Ser-Ser-4-氨基苄酰胺
肽合成中的结构单元。用于通过 β-内酯合成各种 α-氨基酸的原料。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Synthesis of cyclic peptides via O-N-acyl migration.
Lecaillon J, et al.
Tetrahedron Letters, 49(31), 4674-4676 (2008)
Gema Villa-Fombuena et al.
Development (Cambridge, England), 148(18) (2021-08-10)
Drosophila female germline stem cells (GSCs) are found inside the cellular niche at the tip of the ovary. They undergo asymmetric divisions to renew the stem cell lineage and to produce sibling cystoblasts that will in turn enter differentiation. GSCs
O García-Suárez et al.
Immunology, 94(2), 235-241 (1998-09-19)
Increasing evidence suggests that some members of the neurotrophic factor family of neurotrophins could be implicated in the regulation of immune responses. Neurotrophins, as well as their tyrosine kinase signal-transducing receptors (the so-called Trk neurotrophin receptors), have been detected in
Yutaka Matsubayashi et al.
Developmental cell, 54(1), 33-42 (2020-06-26)
The extracellular matrix (ECM) is a polymer network hypothesized to form a stable cellular scaffold. While the ECM can undergo acute remodeling during embryogenesis, it is experimentally difficult to determine whether basal turnover is also important. Most studies of homeostatic
Juulia H Lautaoja et al.
Biomolecules, 10(5) (2020-05-06)
Alongside in vivo models, a simpler and more mechanistic approach is required to study the effects of myostatin on skeletal muscle because myostatin is an important negative regulator of muscle size. In this study, myostatin was administered to murine (C2C12)
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