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Merck
CN

15490

Sigma-Aldrich

Boc-Pro-OH

≥99.0% (T)

别名:

N-(叔丁氧羰基)-L-脯氨酸, Boc-L-脯氨酸

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About This Item

经验公式(希尔记法):
C10H17NO4
CAS号:
分子量:
215.25
Beilstein:
15828
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥99.0% (T)

表单

solid

旋光性

[α]20/D −61±2°, c = 2% in acetic acid

反应适用性

reaction type: Boc solid-phase peptide synthesis

mp

133-135 °C (lit.)

应用

peptide synthesis

SMILES字符串

CC(C)(C)OC(=O)N1CCC[C@H]1C(O)=O

InChI

1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m0/s1

InChI key

ZQEBQGAAWMOMAI-ZETCQYMHSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Manos Gkikas et al.
Biomacromolecules, 16(11), 3686-3693 (2015-10-16)
Novel poly(L-lysine)-block-poly(L-proline) (PLL-b-PLP)-based materials with all PLP helical conformers, i.e., PLP II and the rare PLP I are here reported. Electrostatic supramolecular complexation of the adjacent cationic PLL with anionic molecules bearing DNA analogue H-bonding functionalities, such as deoxyguanosine monophosphate
Griet Van Zeebroeck et al.
Nature chemical biology, 5(1), 45-52 (2008-12-09)
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid analogs to identify compounds that act on Gap1

商品

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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